Georgia Karanasiou S, Nikolaos Tachos S, Sakellarios Antonios, Conway Claire, Pennati Giancarlo, Petrini Lorenza, Lampros Michalis K, Elazer Edelman R, Dimitrios Fotiadis I
Annu Int Conf IEEE Eng Med Biol Soc. 2018 Jul;2018:4567-4570. doi: 10.1109/EMBC.2018.8513205.
Coronary artery disease (CAD) remains the leading cause of death in Europe and worldwide. One of the most common pathologic processes involved in CAD is atherosclerosis. Coronary stents are expandable scaffolds that are used to widen the occluded arteries and enable the blood flow restoration. To achieve an adequate delivery and placement of coronary stents different parameters play a significant role. Due to the strain that the stents are exposed to and the forces they should withstand, the stent design is dominant. This study focuses on investigating the effect of the stent design in two finite element models using two stents with difference in the strut thickness. The in silico deployment is performed in a reconstructed patient specific arterial segment. The results are analyzed in terms of stress in the stent and the arterial wall and demonstrate how stent expansion is extensively affected by the scaffold's design.
冠状动脉疾病(CAD)仍然是欧洲乃至全球的主要死因。CAD所涉及的最常见病理过程之一是动脉粥样硬化。冠状动脉支架是可扩张的支架,用于拓宽闭塞的动脉并恢复血流。为了实现冠状动脉支架的充分输送和放置,不同的参数起着重要作用。由于支架所承受的应变以及它们应承受的力,支架设计起主导作用。本研究聚焦于在两个有限元模型中使用两种支柱厚度不同的支架来研究支架设计的影响。在重建的患者特异性动脉节段中进行计算机模拟展开。根据支架和动脉壁中的应力对结果进行分析,并展示支架扩张如何受到支架设计的广泛影响。