Shen Xiang, Jiang Jiabao, Deng Yongquan, Zhu Hongfei, Lu Kaikai
School of Mechanical Engineering, Jiangsu University, Zhenjiang, 212013, Jiangsu, China.
Cardiovasc Eng Technol. 2019 Dec;10(4):583-589. doi: 10.1007/s13239-019-00437-y. Epub 2019 Oct 15.
In-stent restenosis (ISR) is related to local haemodynamics in the arteries after stent intervention. However, the haemodynamics of stents implanted into tapered vessels is rarely studied and remains unclear. This study aimed to study the haemodynamic performance of a stent in a tapered artery to reveal the haemodynamic differences between tapered and cylindrical stents after stent implantation and guide the stent selection for the treatment of coronary artery stenosis.
Cylindrical and tapered stents were implanted into the tapered arteries. A model of a cylindrical stent implanted into a cylindrical artery was established as the contrast model. Using the finite element method, the flow velocity and wall shear stress distribution of the three models were compared.
At t, t, t and t, the flow rate of the tapered artery with tapered stents (TT) after the implantation increased by 8.59, 3.80, 12.81 and 3.66%, respectively. In addition, the wall shear stress in the tapered arteries of TT was 23.48, 36.67, 13.00 and 8.06% higher than that of the tapered arteries with cylindrical stents (TC).
The implantation of a tapered stent in the tapered artery can effectively improve intravascular haemodynamics. The tapered stent allows the tapered artery to obtain better haemodynamics and reduces the probability of ISR.
支架内再狭窄(ISR)与支架置入术后动脉局部血流动力学有关。然而,锥形血管内植入支架的血流动力学很少被研究,仍不清楚。本研究旨在研究锥形动脉中支架的血流动力学性能,以揭示支架植入后锥形支架与圆柱形支架之间的血流动力学差异,并指导冠状动脉狭窄治疗中支架的选择。
将圆柱形和锥形支架植入锥形动脉。建立圆柱形支架植入圆柱形动脉的模型作为对照模型。采用有限元方法,比较三种模型的流速和壁面剪应力分布。
在t、t、t和t时,植入后带锥形支架的锥形动脉(TT)的血流量分别增加了8.59%、3.80%、12.81%和3.66%。此外,TT锥形动脉中的壁面剪应力比带圆柱形支架的锥形动脉(TC)高23.48%、36.67%、13.00%和8.06%。
在锥形动脉中植入锥形支架可有效改善血管内血流动力学。锥形支架使锥形动脉获得更好的血流动力学,降低了ISR的发生率。