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柔性磁共振成像兼容脑探针。

Flexible MRI Compatible Brain Probes.

作者信息

Ahmadi M, Cruttenden C, Zhu X H, Chen W, Rajamani R

出版信息

Annu Int Conf IEEE Eng Med Biol Soc. 2018 Jul;2018:4579-4582. doi: 10.1109/EMBC.2018.8513162.

Abstract

The exact localization of signal recording probes or deep stimulation probes by magnetic resonance imaging (MRI) has significant importance in studying and understanding how the brain functions. But the magnetic susceptibility of the probes itself distorts the MRI image and creates error in position measurement. In this paper we propose an MRI compatible flexible probe with magnetic susceptibility that is well matched with the brain tissue. The well-matched magnetic susceptibility of the probe enables high resolution structural and functional MRI even at ultra-high Bfield strengths. The MRI images shows almost zero artifacts around the implanted probe in the phantom tissue.

摘要

通过磁共振成像(MRI)对信号记录探针或深部刺激探针进行精确的定位,对于研究和理解大脑功能具有重大意义。但探针本身的磁化率会扭曲MRI图像,并在位置测量中产生误差。在本文中,我们提出了一种具有与脑组织良好匹配的磁化率的MRI兼容柔性探针。该探针良好匹配的磁化率即使在超高磁场强度下也能实现高分辨率的结构和功能MRI。MRI图像显示在模拟组织中植入的探针周围几乎没有伪影。

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