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真性女性压力性尿失禁的神经生理异常

Neurophysiological abnormalities in genuine female stress urinary incontinence.

作者信息

Varma J S, Fidas A, McInnes A, Smith A N, Chisholm G D

机构信息

Western General Hospital, Edinburgh.

出版信息

Br J Obstet Gynaecol. 1988 Jul;95(7):705-10. doi: 10.1111/j.1471-0528.1988.tb06534.x.

DOI:10.1111/j.1471-0528.1988.tb06534.x
PMID:3415936
Abstract

Perineal sensory and motor function was investigated in 28 women with genuine stress incontinence of urine and compared with a matched control group. Electrosensitivity of the dorsal nerve of the clitoris and of the urethral mucosa was significantly diminished in these patients (eight measurements 'insensitive'). Three different reflex latency measurements (dorsal nerve to external anal sphincter, dorsal nerve to urethral sphincter, urethral mucosa to external anal sphincter) were prolonged in incontinence (14 absent reflexes). Mean motor unit potential duration of the external anal sphincter was also prolonged, reflecting an early neuropathy. Anorectal manometry detected significantly weaker squeeze pressures in stress incontinence although other variables were unaffected.

摘要

对28名真性压力性尿失禁女性的会阴感觉和运动功能进行了研究,并与匹配的对照组进行比较。这些患者阴蒂背神经和尿道黏膜的电敏感性显著降低(8次测量为“无反应”)。三种不同的反射潜伏期测量(阴蒂背神经至肛门外括约肌、阴蒂背神经至尿道括约肌、尿道黏膜至肛门外括约肌)在尿失禁患者中延长(14次反射缺失)。肛门外括约肌的平均运动单位电位持续时间也延长,提示早期神经病变。肛门直肠测压法检测到压力性尿失禁患者的收缩压明显较弱,尽管其他变量未受影响。

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Electrophysiological evaluation of the pudendal nerve and urethral innervation in female stress urinary incontinence.女性压力性尿失禁患者阴部神经及尿道神经支配的电生理评估
Int Urogynecol J. 2013 May;24(5):801-7. doi: 10.1007/s00192-012-1931-8. Epub 2012 Sep 8.
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Urethral sensory threshold and urethro-anal reflex latency in continent women.
Int Urol Nephrol. 2007;39(4):1061-8. doi: 10.1007/s11255-007-9177-y. Epub 2007 Mar 6.
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A regional audit of the investigation and treatment of colorectal and pelvic floor disorders (1984-1991).一项关于结直肠和盆底疾病调查与治疗的区域审计(1984 - 1991年)
Int J Colorectal Dis. 1993 Jul;8(2):66-70. doi: 10.1007/BF00299329.
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Br J Gen Pract. 1993 Oct;43(375):426-9.