Chung Eugene, Karlberg Helena I
Department of Anesthesiology, Perioperative and Pain Medicine, Texas Children's Hospital, Baylor College of Medicine, Houston, TX.
J Craniofac Surg. 2019 Jan;30(1):186-187. doi: 10.1097/SCS.0000000000004905.
Pediatric craniosynostosis repair with cranial vault reconstructive surgery can be associated with significant blood loss. Tranexamic acid (TXA), an antifibrinolytic agent, has been shown to decrease blood loss and transfusion volume in craniofacial surgery. Nonetheless data regarding the safety of TXA remains limited. The authors describe a case of ulnar artery thrombosis following ulnar arterial line placement in a patient who received TXA for cranial vault reconstructive surgery.
小儿颅骨缝早闭修复术联合颅骨穹窿重建手术可能会导致大量失血。氨甲环酸（TXA）是一种抗纤溶药物，已被证明可减少颅面外科手术中的失血量和输血量。然而，关于TXA安全性的数据仍然有限。作者描述了一例在接受TXA进行颅骨穹窿重建手术的患者中，尺动脉置管后发生尺动脉血栓形成的病例。
