Department of Mental Health, Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Osun State, Nigeria.
Department of Mental Health, State Specialist Hospital, Osogbo, Osun State, Nigeria.
Gen Hosp Psychiatry. 2018 Nov-Dec;55:72-76. doi: 10.1016/j.genhosppsych.2018.07.003. Epub 2018 Sep 2.
Obsessive compulsive symptoms (OCS) are relatively common in schizophrenia. Their presence and severity can affect the quality of life (QoL) of schizophrenia patients.
This study aimed to determine the effect of OCS on the subjective QoL of the Nigerian outpatients with schizophrenia. It also determines the sociodemographic and clinical factors associated with OCS.
A cross-sectional study involving 232 patients with schizophrenia completed socio-demographic and clinical characteristics questionnaire. OCS was examined with Obsessive Compulsive Inventory (OCI) and QoL was assessed using the brief version of the World Health Organisation Quality of Life questionnaire.
Most of the schizophrenia patients with OCS were unmarried, unemployed, had an earlier onset, longer duration of illness, and were on higher doses of antipsychotics. They reported lower QoL and more severity of symptoms of schizophrenia when compared to those without OCS. The OCI total and it's subscales had negative weak to moderate relationship with all the domains of the WHOQoL Bref. Being unemployed, dosage of antipsychotic medication, negative symptoms and OCI total were the predictors of the total quality of life among Nigerian schizophrenia patients.
OCS are very common and reduce QoL of schizophrenia patients. Hence, there is a need to routinely screen patients with schizophrenia for OCS and manage them appropriately.
强迫症症状(OCS)在精神分裂症中较为常见。其存在和严重程度可能会影响精神分裂症患者的生活质量(QoL)。
本研究旨在确定 OCS 对尼日利亚门诊精神分裂症患者主观 QoL 的影响。还确定与 OCS 相关的社会人口学和临床因素。
一项横断面研究涉及 232 名精神分裂症患者,完成了社会人口学和临床特征问卷。使用强迫症清单(OCI)检查 OCS,使用世界卫生组织生活质量问卷的简短版本评估 QoL。
大多数有 OCS 的精神分裂症患者未婚、失业、发病较早、病程较长、服用较高剂量的抗精神病药物。与没有 OCS 的患者相比,他们报告的生活质量较低,精神分裂症症状更严重。OCI 总分及其分量表与 WHOQoL Bref 的所有领域均呈负弱到中度相关。失业、抗精神病药物剂量、阴性症状和 OCI 总分是尼日利亚精神分裂症患者总体生活质量的预测因素。
OCS 非常常见,会降低精神分裂症患者的生活质量。因此,有必要定期对精神分裂症患者进行 OCS 筛查并进行适当的治疗。