Hildebrandt Christiane, Mayer Hanna, Koller Antje
Department of Nursing Science, University of Vienna, Vienna, Austria.
Psychooncology. 2019 Feb;28(2):219-227. doi: 10.1002/pon.4946. Epub 2018 Dec 28.
The purpose of this meta-synthesis was to explore the experience of living with symptoms caused by colorectal cancer (CRC) and its treatment from the perspectives of those affected.
In a systematic search of qualitative studies published up to September 2017, 21 relevant papers were identified. The meta-ethnography followed the approach developed by Noblit and Hare. To relate key themes from one paper to similar themes of different papers, a "reciprocal translation" was carried out.
Through synthesis, a new model was developed during treatment ("lines-of-argument synthesis"). Two constructs of experiences took place before the illness. Six third-order constructs were developed to capture patients' experiences during treatment, including "disruption in life through CRC" as well as the complex and circular experiences summarized as "experiences of symptoms and challenges by CRC". In contrast, experiences in dealing with changes that CRC and the treatment imply were "making sense of the experience", "sharing the experience", "experiences with controlling ones' body", and "experiences with reforming life".
This meta-ethnography clarifies fundamental aspects of patients' experience in very different settings or starting points by specifying a more complete and holistic spectrum of experiences with CRC and its treatment.
本元综合研究旨在从患者角度探讨结直肠癌（CRC）及其治疗所引发症状的生活体验。
在对截至2017年9月发表的定性研究进行系统检索时，共识别出21篇相关论文。元民族志研究遵循诺布利特和黑尔所提出的方法。为将一篇论文中的关键主题与不同论文的相似主题联系起来，进行了“相互翻译”。
通过综合分析，在治疗过程中形成了一个新模型（“论证线综合”）。在患病前出现了两种体验结构。为捕捉患者在治疗期间的体验，开发了六个三阶结构，包括“CRC导致的生活中断”以及概括为“CRC的症状和挑战体验”的复杂循环体验。相比之下，应对CRC及其治疗所带来变化的体验包括“理解体验”“分享体验”“身体控制体验”和“生活重塑体验”。
本元民族志通过明确更完整、更全面的CRC及其治疗体验范围，阐明了患者在非常不同的背景或起点下体验的基本方面。
