Odish M, Chen M, Kim A, Floreth T
Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University of California-San Diego, San Diego, California.
Division of Rheumatology, Allergy, and Immunology, Department of Medicine, University of California-San Diego, San Diego, California.
Transplant Proc. 2018 Dec;50(10):4085-4086. doi: 10.1016/j.transproceed.2018.08.001. Epub 2018 Aug 9.
This case report describes a patient who acquired a donor peanut allergy after lung transplantation. A 53-year-old woman with alpha-1 antitrypsin deficiency underwent left-sided lung transplant from a donor with a history of anaphylaxis to peanut. Two weeks after the transplant, the patient developed acute respiratory failure immediately after consuming a peanut butter and jelly sandwich. The donor's serum confirmed high titers of peanut-specific immunoglobulin E (IgE). The recipient patient had never had allergies to peanuts or other nuts before her transplant. After the transplant, she had negative serology but positive skin testing to peanuts. This case illustrates the importance of considering donor food allergies when caring for solid organ transplant recipients.
本病例报告描述了一名肺移植后获得供体花生过敏的患者。一名患有α-1抗胰蛋白酶缺乏症的53岁女性接受了来自有花生过敏反应病史供体的左侧肺移植。移植两周后，患者在食用花生酱和果冻三明治后立即出现急性呼吸衰竭。供体血清证实花生特异性免疫球蛋白E（IgE）滴度很高。受体患者在移植前从未对花生或其他坚果过敏。移植后，她的血清学检测呈阴性，但花生皮肤试验呈阳性。该病例说明了在照顾实体器官移植受者时考虑供体食物过敏的重要性。
