Histone hyperacetylation is induced in chick erythrocyte nuclei during reactivation in heterokaryons.
作者信息
Pfeffer U, Ferrari N, Tosetti F, Vidali G
机构信息
Laboratory of Molecular Biology, Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy.
出版信息
Exp Cell Res. 1988 Sep;178(1):25-30. doi: 10.1016/0014-4827(88)90374-6.
PMID:3044809
Abstract
Transcriptionally inactive avian red blood cell nuclei were reactivated by Sendai virus-induced fusion of chicken erythrocytes with HeLa cells. We have used antibodies which specifically recognize the tetraacetylated form of H4 histone to show that histone hyperacetylation is an event required for chromatin reorganization leading to a transcriptionally competent chromatin structure.
摘要
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