Blagosklonny Mikhail V
Cell Stress Biology, Roswell Park Cancer Institute, Buffalo, NY 14263, USA.
Aging (Albany NY). 2018 Nov 17;10(11):3067-3078. doi: 10.18632/aging.101647.
Is aging a disease? It does not matter because aging is already treated using a combination of several clinically-available drugs, including rapamycin. Whether aging is a disease depends on arbitrary definitions of both disease and aging. For treatment purposes, aging is a deadly disease (or more generally, pre-disease), despite being a normal continuation of normal organismal growth. It must and, importantly, can be successfully treated, thereby delaying classic age-related diseases such as cancer, cardiovascular and metabolic diseases, and neurodegeneration.
衰老算是一种疾病吗?这无关紧要,因为衰老已经在通过使用几种临床可用药物(包括雷帕霉素)的组合进行治疗。衰老是否是一种疾病取决于对疾病和衰老的任意定义。出于治疗目的,衰老尽管是正常生物体生长的正常延续,但却是一种致命疾病(或者更普遍地说,是疾病前期)。它必须且重要的是能够被成功治疗,从而延缓诸如癌症、心血管疾病、代谢疾病和神经退行性变等典型的与年龄相关的疾病。