Department of Pathology, Cleveland Clinic, Cleveland, Ohio.
Department of Breast Surgery, Cleveland Clinic, Cleveland, Ohio.
Breast J. 2019 Jan;25(1):80-85. doi: 10.1111/tbj.13160. Epub 2018 Nov 17.
Granulomatous mastitis is an uncommon inflammatory disease that typically presents with painful breast lesions. Recent publications have brought to light a specific subset of granulomatous mastitis patients with a distinct histological pattern of disease termed, "cystic neutrophilic granulomatous mastitis" (CNGM). Although many cases of granulomatous lobular mastitis have been thought to be idiopathic, this rare subset of an uncommon disease has been linked to infections with Corynebacterium species. Herein, a cohort of CNGM patients from a large, tertiary care, North-American, academic medical center is presented. Correlative demographic, clinical, radiographic, pathologic, microbiologic, management, and outcomes data are provided. Collaborative communication between specialists to accurately diagnose and manage these patients is essential to decreasing potential morbidity.
肉芽肿性乳腺炎是一种不常见的炎症性疾病，通常表现为疼痛的乳腺病变。最近的出版物揭示了一类特定的肉芽肿性乳腺炎患者，其具有一种称为“囊性中性粒细胞性肉芽肿性乳腺炎”（CNGM）的独特组织病理学模式。尽管许多肉芽肿性小叶性乳腺炎病例被认为是特发性的，但这种罕见的不常见疾病的罕见亚组与棒状杆菌属感染有关。本文介绍了来自一家大型北美学术医疗中心的 CNGM 患者队列。提供了相关的人口统计学、临床、影像学、病理学、微生物学、管理和结果数据。专家之间的协作沟通对于准确诊断和管理这些患者至关重要，可降低潜在的发病率。
