皮肤赘生物是结肠息肉的一个标志吗？一项针对100例无症状患者的前瞻性研究及文献荟萃分析。

Do skin tags constitute a marker for colonic polyps? A prospective study of 100 asymptomatic patients and metaanalysis of the literature.

作者信息

Piette A M, Meduri B, Fritsch J, Fermanian J, Piette J C, Chapman A

机构信息

Service de Médecine Interne, Centre Médico-Chirurgical, Foch, Suresnes, France.

出版信息

Gastroenterology. 1988 Oct;95(4):1127-9. doi: 10.1016/0016-5085(88)90193-x.

DOI:10.1016/0016-5085(88)90193-x

PMID:3044909

Abstract

Several reports have suggested that skin tags may be a marker for the presence of colonic polyps in symptomatic patients referred for colonoscopy. In a prospective study of 100 asymptomatic patients, we found no association between skin tags and colonic polyps. A review of the literature and results of a metaanalysis show a significant association between skin tags and colonic polyps in 777 symptomatic patients, but no association in 268 asymptomatic patients. To explain this discrepancy, several possible biases are analyzed. As skin tags constitute a marker for colonic polyps only in symptomatic patients for whom a colonoscopy is already indicated, their detection is of no diagnostic value in asymptomatic patients.

摘要

几份报告表明，在因结肠镜检查而就诊的有症状患者中，皮肤赘生物可能是结肠息肉存在的一个标志。在一项对100名无症状患者的前瞻性研究中，我们发现皮肤赘生物与结肠息肉之间没有关联。文献综述和一项荟萃分析的结果显示，在777名有症状的患者中，皮肤赘生物与结肠息肉之间存在显著关联，但在268名无症状患者中没有关联。为了解释这种差异，分析了几种可能的偏倚。由于皮肤赘生物仅在已被建议进行结肠镜检查的有症状患者中构成结肠息肉的一个标志，所以它们的检出对无症状患者没有诊断价值。