通过对免疫印迹法确认的样本进行系列稀释，比较10种HIV抗体检测试验的灵敏度。
Comparison in sensitivity of 10 HIV antibody detection tests by serial dilutions of Western blot-confirmed samples.
作者信息
Stute R
机构信息
Blutbank Saarland, Staatliches Institut für Gesundheid und Umwelt, Saarbrücken, F.R.G.
出版信息
J Virol Methods. 1988 Jul;20(3):269-74. doi: 10.1016/0166-0934(88)90130-9.
Nine ELISA tests and one particle agglutination test for the detection of HIV antibodies were analysed using serial dilutions of Western blot-confirmed positive serum samples. These samples were diluted in HIV antibody negative human serum in a range of 1:10 to 1:10,000 or 1:100,000. Remarkable differences in sensitivity were observed. Some tests were 10- to 100-fold more sensitive than others, and even differences of 1000-fold were detected.
使用经蛋白质印迹法确认的阳性血清样本的系列稀释液，对九种用于检测HIV抗体的酶联免疫吸附测定（ELISA）试验和一种颗粒凝集试验进行了分析。这些样本在HIV抗体阴性的人血清中按1:10至1:10,000或1:100,000的比例进行稀释。观察到了显著的灵敏度差异。一些试验的灵敏度比其他试验高10至100倍，甚至检测到了1000倍的差异。
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