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巴西塞尔希培州前列腺癌死亡率的趋势与空间分析。

Trend and spatial analysis of prostate cancer mortality in the state of Sergipe, Brazil.

作者信息

Góes José Augusto Passos, Souza Danilo De Gois, Andrade Lucas Almeida, Cunha Jéssica, Kameo Simone, Góes Marco Aurélio O, De Menezes Andreia Freire, Nunes Marco Antônio P, Machado de Araújo Karina Conceiçao Gomes, Santos Allan D

机构信息

Department of Nursing, Federal University of Sergipe, Sergipe.

出版信息

Geospat Health. 2018 Nov 12;13(2). doi: 10.4081/gh.2018.732.

DOI:10.4081/gh.2018.732
PMID:30451478
Abstract

This is an ecological study with exploratory analysis of spatial and temporal data based on mortality data with respect to prostate cancer obtained from the Mortality Information System concerning residents of the state of Sergipe, Brazil between 2000 and 2015. The analysis of temporal trends was performed using the Joinpoint Regression Program through Poisson regression. Spatial analysis was performed using the empirical Bayesian model, Kernel analysis, Global Moran and Local indices. There were 1,986 deaths due to prostate cancer, most of which occurring after 60 years of age. An increasing, non-constant but significant trend in mortality rates was noted. The kernel density estimator showed hotspot densities of the highest rates of prostate cancer mortality in the north-eastern and central regions of the state. High-risk clusters were identified for prostate cancer mortality (I = 0.55, P<0.01). There was an increase in prostate cancer mortality rates and a heterogeneous geographic distribution of risk areas, with high-risk priority areas identified in certain regions of the state. These priority areas include the municipalities located in the Northeast (Amparo do São Francisco, Aquidabã, Canhoba, Cedro de São João and Telha), the West (Frei Paulo and Pedra Mole) and the south-western region of the state (Poço Verde and Simão Dias).

摘要

这是一项生态学研究,基于2000年至2015年期间从巴西塞尔希培州居民死亡率信息系统获取的前列腺癌死亡率数据,对空间和时间数据进行探索性分析。使用Joinpoint回归程序通过泊松回归进行时间趋势分析。使用经验贝叶斯模型、核分析、全局莫兰指数和局部指数进行空间分析。前列腺癌死亡病例有1986例,其中大多数发生在60岁以后。观察到死亡率呈上升趋势,虽非恒定但具有显著性。核密度估计显示该州东北部和中部地区前列腺癌死亡率最高的热点密度。确定了前列腺癌死亡率的高风险聚集区(I = 0.55,P<0.01)。前列腺癌死亡率上升,风险区域地理分布不均,该州某些地区确定了高风险优先区域。这些优先区域包括位于东北部的城市(圣弗朗西斯科的安帕罗、阿基达巴、坎霍巴、圣若昂的塞德罗和特尔哈)、西部的城市(弗雷·保罗和佩德拉·莫莱)以及该州西南部地区(波苏韦尔德和西芒·迪亚斯)。

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