Neal Lauren B, Gable Philip A
Department of Psychology, The University of Alabama, 505 Hackberry Lane, P.O. Box 870348, Tuscaloosa, AL, 35487-0348, United States.
Biol Psychol. 2019 Jan;140:28-34. doi: 10.1016/j.biopsycho.2018.11.002. Epub 2018 Nov 16.
The frontal cortices are asymmetrically activated in impulsive and inhibitory action. However, no past work has examined shifts in frontal asymmetric activation during active impulse control or risk-taking behavior. The current study examined impulsive and controlled behavior in a behavioral risk-taking task (Balloon Analogue Risk Task) under alcohol or neutral cue exposure while EEG was recorded. Results revealed activity shifted towards greater relative left frontal activation on alcohol trials with impulsive behavior (balloon explosion) driven by reduced activation of the right inferior frontal gyrus. In contrast, activity from the first half to the second half of alcohol trials with successful impulse control (cash out) localized to reduced activation of the left inferior frontal gyrus. These findings suggest that shifting of right or left frontal asymmetry in inhibitory or impulsive behaviors stem from activation of the inferior frontal gyrus and reveal the importance of examining shifts in neural activity during behavioral processes.
前额叶皮质在冲动和抑制行为中呈不对称激活。然而，以往的研究均未考察在主动冲动控制或冒险行为过程中前额叶不对称激活的变化。本研究在记录脑电图的同时，考察了在酒精或中性线索暴露条件下，行为冒险任务（气球模拟风险任务）中的冲动和控制行为。结果显示，在酒精试验中，冲动行为（气球爆炸）导致相对左前额叶激活增强，这是由右下前额叶回激活减少所致。相反，在酒精试验中，成功进行冲动控制（兑现）的前半段到后半段的活动定位于左下前额叶回激活减少。这些发现表明，抑制或冲动行为中右或左前额叶不对称的变化源于下前额叶回的激活，并揭示了在行为过程中检查神经活动变化的重要性。
