Ozpak Berkan, Yilmaz Yeliz
1 Department of Cardiovascular Surgery, Çorlu State Hospital, Tekirdağ, Turkey.
2 Department of General Surgery, İzmir Katip Celebi University, Ataturk Training and Research Hospital, İzmir, Turkey.
Vascular. 2019 Jun;27(3):270-276. doi: 10.1177/1708538118811483. Epub 2018 Nov 19.
This study aimed to evaluate the effects of hemodialysis catheters on the survival of subsequent arteriovenous fistulas, according to the relative localization to the catheters.
A total of 201 patients who initiated dialysis therapy using a hemodialysis catheter were eligible for this retrospective study. Arteriovenous fistulas were created on the nondominant upper extremity after the placement of hemodialysis catheters. The catheters were removed after four consecutive successful dialyses via arteriovenous fistulas. The effective factors on arteriovenous fistula failure were determined in and the prognostic factors for survival were modeled by regression analysis.
The relative placement of catheters as ipsi- or contralateral was found to significantly affect the survival of the arteriovenous fistulas. The overall survival was significantly longer in the contralateral arteriovenous fistula group (778.7 ± 28.8 vs. 247.3 ± 26.1 days; p < 0.001). The independent predictors of arteriovenous fistula survival were found to be relative side of arteriovenous fistula and hemodialysis catheter, age, and the presence of hypertension in multivariate analyses.
This study showed that ipsilateral localization of the catheters and arteriovenous fistulas negatively affect the cumulative arteriovenous fistula survival. Therefore, to improve vascular access survival, side of catheters or arteriovenous fistulas should always be considered.
本研究旨在根据血液透析导管与动静脉内瘘的相对位置,评估血液透析导管对后续动静脉内瘘存活情况的影响。
共有201例开始使用血液透析导管进行透析治疗的患者符合本回顾性研究的条件。在放置血液透析导管后,于非优势上肢建立动静脉内瘘。在通过动静脉内瘘连续成功进行4次透析后,拔除导管。确定影响动静脉内瘘失败的有效因素,并通过回归分析建立存活的预后因素模型。
发现导管同侧或对侧的相对位置对动静脉内瘘的存活有显著影响。对侧动静脉内瘘组的总体存活时间明显更长(778.7±28.8天对247.3±26.1天;p<0.001)。在多因素分析中,发现动静脉内瘘存活的独立预测因素为动静脉内瘘与血液透析导管的相对位置、年龄以及是否存在高血压。
本研究表明,导管与动静脉内瘘同侧定位会对动静脉内瘘的累积存活产生负面影响。因此,为提高血管通路的存活时间,应始终考虑导管或动静脉内瘘的位置。