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一项评估术前经皮导管引流治疗腰椎结核伴腰大肌脓肿可行性的对比研究。

A comparative study to evaluate the feasibility of preoperative percutaneous catheter drainage for the treatment of lumbar spinal tuberculosis with psoas abscess.

作者信息

Lai Zhen, Shi Shiyuan, Fei Jun, Han Guihe, Hu Shengping

机构信息

Department of Orthopedics, Hospital of Integrated Traditional Chinese and Western medicine in Zhejiang Province, 208 Huancheng E.Rd, Hangzhou, 310003, Zhejiang Province, People's Republic of China.

出版信息

J Orthop Surg Res. 2018 Nov 19;13(1):290. doi: 10.1186/s13018-018-0993-9.

Abstract

BACKGROUND

Spinal tuberculosis is a frequent cause of psoas abscess (PA), and PA largely negates the efficacy of antituberculosis therapy. This study aimed to investigate the clinical outcome of preoperative percutaneous catheter drainage (PCD) in patients with lumbar spinal tuberculosis and PA.

METHODS

Between January 2015 and January 2017, 72 patients with lumbar spinal tuberculosis with PA were assigned to group A (preoperative PCD) and group B (n = 36 per group). All patients received posterior pedicle screw fixation and anterior focal debridement and fusion. Data on intraoperative blood loss, the duration of the surgery, and the length of the anterior incision were recorded, as well as the postoperative anal exhaust time, visual analogue scale (VAS), Cobb angle, lumbar vertebra function, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) level, and sinus tract formation.

RESULTS

Sixty-eight patients were followed up for an average time of 13 months (range 6-21 months). Until the final follow-up, no mixed infections, recurrence of tuberculosis, pedicle screw loosening, or screw pullout had occurred. There were significant between-group differences in blood loss, surgery duration, anterior incisional length, postoperative anal exhaust time, and sinus tract formation. As compared with group B, the ESR and CRP levels of the patients in group A were markedly improved following 3 weeks of antituberculosis therapy and 1 week postsurgery.

CONCLUSION

Preoperative PCD helps to increase the efficacy of antituberculosis therapy prior to surgery, reduce surgical trauma, and avoid postoperative complications, making it a safe and feasible treatment option for lumbar spinal tuberculosis with PA.

摘要

背景

脊柱结核是腰大肌脓肿(PA)的常见病因,而PA在很大程度上会降低抗结核治疗的疗效。本研究旨在探讨术前经皮导管引流(PCD)对腰椎结核合并PA患者的临床疗效。

方法

2015年1月至2017年1月期间,将72例腰椎结核合并PA患者分为A组(术前PCD)和B组(每组36例)。所有患者均接受后路椎弓根螺钉固定及前路病灶清除融合术。记录术中失血量、手术时间、前切口长度,以及术后肛门排气时间、视觉模拟评分(VAS)、Cobb角、腰椎功能、红细胞沉降率(ESR)、C反应蛋白(CRP)水平和窦道形成情况。

结果

68例患者获得随访,平均随访时间为13个月(范围6 - 21个月)。至末次随访时,未发生混合感染、结核复发、椎弓根螺钉松动或拔出。两组在失血量、手术时间、前切口长度、术后肛门排气时间和窦道形成方面存在显著差异。与B组相比,A组患者在抗结核治疗3周及术后1周后,ESR和CRP水平明显改善。

结论

术前PCD有助于提高术前抗结核治疗的疗效,减少手术创伤,避免术后并发症,是腰椎结核合并PA的一种安全可行的治疗选择。

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