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一期后路横突间病灶清除、椎间孔入路植骨融合内固定术治疗腰椎结核合并腰大肌脓肿

Single-stage posterior resection of the transversal process combined with an intervertebral foraminal approach for debridement, interbody fusion, internal fixation for the treatment of lumbar tuberculosis and psoas major abscess.

机构信息

Comprehensive Surgery (Special Surgery), First Affiliated Hospital of Xinjiang Medical University, No. 137 South Liyushan Road, Urumqi, China.

College of Nursing, Xinjiang Medical University, Urumqi, China.

出版信息

Int Orthop. 2022 Feb;46(2):331-339. doi: 10.1007/s00264-021-05244-6. Epub 2021 Oct 25.

Abstract

PURPOSES

To investigate the feasibility and clinical efficacy of the treatment for lumbar tuberculosis with psoas major abscess with single-stage posterior resection of the transversal process combined with an intervertebral foraminal approach for debridement, interbody fusion, internal fixation.

METHODS

This retrospective study evaluated the clinical data of 24 patients (14 males and 10 females) with lumbar tuberculosis and psoas major abscess admitted to the Comprehensive Surgery from June 2016 to June 2019. All patients were treated with the single-stage posterior approach to remove the transverse process combined with the intervertebral foramina approach for debridement, interbody fusion, internal fixation. The quadruple anti-tuberculosis drug therapy was given both pre-operatively and post-operatively. Clinical symptoms and complications were investigated and recorded. The visual analogue scale (VAS), American Spinal Injury Association (ASIA), degree of lesion fusion C-reactive protein (CRP) levels, and erythrocyte sedimentation rate (ESR) were evaluated.

RESULTS

The average follow-up period was 16. 5 months (from 12 to 36 months). The average VAS score at three months post-operation was significantly declined than the pre-operative VAS score [(2.17 ± 0.87) points vs (5.46 ± 1.22) points, t =  - 11.534, P < 0.01)]. At the last follow-up, the neurological function of 20 patients recovered to grade E, whereas four patients were still in grade D. The ESR and CRP returned to normal levels in all patients. Bone fusion was achieved in nine cases at six months, 11 cases at nine months, and four cases at 12 months. The incisions of 23 patients had healed nicely without chronic sinus. Poor incision healing only happened in one case at the day 12 post-operation. The bone grafts among the lesions obtained bony fusion. Besides, there was no recurrence of tuberculosis, loosening or fracture of internal fixation during the follow-up.

CONCLUSION

Single-stage posterior resection of the transversal process combined with an intervertebral foramina approach for debridement, interbody fusion, internal fixation is probably an effective and safe approach of the treatment for lumbar tuberculosis combined with psoas major abscess, producing few complications. This technique provides an alternative method for the surgical treatment of lumbar tuberculosis combined with psoas major abscess.

摘要

目的

探讨一期后路横突切除联合椎间孔入路病灶清除、椎间植骨融合内固定治疗腰椎结核合并腰大肌脓肿的可行性及临床疗效。

方法

回顾性分析 2016 年 6 月至 2019 年 6 月收治的 24 例腰椎结核合并腰大肌脓肿患者的临床资料,男 14 例,女 10 例;均采用一期后路横突切除联合椎间孔入路病灶清除、椎间植骨融合内固定术治疗,术前及术后均给予四联抗结核药物治疗。观察记录患者的临床症状及并发症,采用视觉模拟评分(VAS)、美国脊髓损伤协会(ASIA)评分、病灶融合程度、C 反应蛋白(CRP)、红细胞沉降率(ESR)评估疗效。

结果

患者平均随访 16.5 个月(12~36 个月)。术后 3 个月 VAS 评分较术前明显下降[(2.17±0.87)分比(5.46±1.22)分,t=-11.534,P<0.01]。末次随访时,20 例患者神经功能恢复至 E 级,4 例仍为 D 级。所有患者 ESR、CRP 均恢复正常。9 例患者术后 6 个月、11 例患者术后 9 个月、4 例患者术后 12 个月融合。23 例患者切口愈合良好,无慢性窦道形成,仅 1 例患者术后 12 d 出现切口愈合不良。病变部位植骨均获得骨性融合,随访过程中未见结核复发、内固定松动或断裂。

结论

一期后路横突切除联合椎间孔入路病灶清除、椎间植骨融合内固定治疗腰椎结核合并腰大肌脓肿,可能是一种有效、安全的方法,并发症少。该技术为腰椎结核合并腰大肌脓肿的手术治疗提供了一种选择。

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