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[胸外科重症患者下肢深静脉血栓形成的发生率及凝血状态]

[Incidence of Lower Limb Deep Venous Thrombosis and Coagulation Status 
in Severe Patients after Thoracic Surgery].

作者信息

Huang Ying, Wang Chunmei, Zhang Yi, Ning Yachan, Kui Libing, Song Lipo, Zhi Xiuyi, Yan Dan, Ji Xunming

机构信息

Department of Vascular Surgery Intensive Care Unit, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.

Department of Thoracic Surgery, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.

出版信息

Zhongguo Fei Ai Za Zhi. 2018 Nov 20;21(11):864-867. doi: 10.3779/j.issn.1009-3419.2018.11.12.

DOI:10.3779/j.issn.1009-3419.2018.11.12
PMID:30454549
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6247009/
Abstract

BACKGROUND

The aim of this study was to analyze the incidence of lower limb deep venous thrombosis (DVT) and the corresponding coagulation status in severe patients after thoracic surgery.

METHODS

Severe patients after thoracic surgery who received mechanical prophylaxis of lower limb DVT between July 2016 and June 2018 were analysed retrospectively. Their general information, disease species, surgical treatment, and coagulation index were reviewed.

RESULTS

Fifty patients were finally included. There were 34 male and 16 female, aging from 22 to 80 years. The incidence of DVT was 22.0%, all of them were isolated calf DVT. The incidence was 29.4% in male patients, while 6.3% in female; 23.5% in malignant diseases and 18.6% in benign. All coagulation index presented no statistical difference between patients with and without DVT, except activated partial thromboplastin time (APTT).

CONCLUSIONS

Even on the basis of adequate mechanical prophylaxis, lower limb DVT is common in severe patients after thoracic surgery. Meanwhile, male patients and malignant diseases are more suscepted.

摘要

背景

本研究旨在分析胸科手术后重症患者下肢深静脉血栓形成(DVT)的发生率及相应的凝血状态。

方法

回顾性分析2016年7月至2018年6月期间接受下肢DVT机械预防的胸科手术后重症患者。对其一般信息、疾病种类、手术治疗及凝血指标进行回顾。

结果

最终纳入50例患者。其中男性34例,女性16例,年龄22至80岁。DVT发生率为22.0%,均为孤立性小腿DVT。男性患者发生率为29.4%,女性为6.3%;恶性疾病患者发生率为23.5%,良性疾病患者为18.6%。除活化部分凝血活酶时间(APTT)外,所有凝血指标在有DVT和无DVT患者之间均无统计学差异。

结论

即使在充分的机械预防基础上,胸科手术后重症患者下肢DVT仍很常见。同时,男性患者和恶性疾病患者更易发生。

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本文引用的文献

1
[Incidence of postoperative venous thromboembolism after thoracic surgery and its characteristic: a single center, prospective cohort study].[胸外科手术后静脉血栓栓塞症的发生率及其特征:一项单中心前瞻性队列研究]
Zhonghua Wai Ke Za Zhi. 2018 Apr 1;56(4):284-288. doi: 10.3760/cma.j.issn.0529-5815.2018.E008.
2
[Survey of current status of prevention of venous thromboembolism after thoracic surgery in China].[中国胸外科手术后静脉血栓栓塞症预防现状调查]
Zhonghua Wai Ke Za Zhi. 2017 Sep 1;55(9):661-666. doi: 10.3760/cma.j.issn.0529-5815.2017.09.005.
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Antithrombotic Therapy for VTE Disease: CHEST Guideline and Expert Panel Report.抗栓治疗 VTE 疾病:CHEST 指南和专家小组报告。
Chest. 2016 Feb;149(2):315-352. doi: 10.1016/j.chest.2015.11.026. Epub 2016 Jan 7.
4
The anticoagulation of calf thrombosis (ACT) project: results from the randomized controlled external pilot trial.小腿血栓抗凝(ACT)项目:随机对照外部试点试验结果。
Chest. 2014 Dec;146(6):1468-1477. doi: 10.1378/chest.14-0235.
5
[The changes of blood coagulation in surgical patients with lung cancer].[肺癌手术患者的血液凝固变化]
Zhongguo Fei Ai Za Zhi. 2010 Feb;13(2):136-9. doi: 10.3779/j.issn.1009-3419.2010.02.11.