Domoradskiĭ I V, Domoradskaia T I
Mol Gen Mikrobiol Virusol. 1988 May(5):3-11.
Adsorption of bacteriophages on the surface of microbial cell is the first link in the chain of events leading to the development of bacteriophage infection. Adsorption is based on the presence of appropriate receptors of the various chemical nature. All the receptors are of significance for cellular metabolism. Some of them have the pathogenicity functions and antigenic properties. In course of bacterial dissociation some receptors disappear and others become available for bacteriophages. It is concluded, with a number of examples supporting the conclusion, that bacteriophages may be used in elucidation of cellular wall characteristics and architectonics as well as for the direct selection of mutant clones. The conclusion is also valid for bacteriocins, although, their chemical nature and location of receptors are not studied enough.
噬菌体在微生物细胞表面的吸附是导致噬菌体感染发生的一系列事件中的第一个环节。吸附基于各种化学性质的合适受体的存在。所有受体对细胞代谢都具有重要意义。其中一些具有致病性功能和抗原特性。在细菌解离过程中,一些受体消失,而其他受体则可供噬菌体利用。有多个例子支持这一结论,即噬菌体可用于阐明细胞壁的特征和结构,以及直接筛选突变克隆。尽管对细菌素的化学性质和受体位置研究得还不够充分,但这一结论对细菌素也同样适用。