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家庭中心肺睡眠研究:在研究和临床队列中的经验。

Cardiorespiratory sleep studies at home: experience in research and clinical cohorts.

机构信息

Sheffield Children's NHS Foundation Trust, Sheffield, UK.

Southampton Children's Hospital, Southampton University NHS Trust, Southampton, UK.

出版信息

Arch Dis Child. 2019 May;104(5):476-481. doi: 10.1136/archdischild-2018-315676. Epub 2018 Nov 19.

DOI:10.1136/archdischild-2018-315676
PMID:30455364
Abstract

OBJECTIVE

To evaluate the success rates of home cardiorespiratory polygraphy in children under investigation for sleep-disordered breathing and parent perspectives on equipment use at home.

DESIGN

Prospective observational study.

SETTING

Sheffield, Evelina London and Southampton Children's Hospitals.

PATIENTS

Data are reported for 194 research participants with Down syndrome, aged 0.5-5.9 years across the three centres and 61 clinical patients aged 0.4-19.5 years from one centre, all of whom had home cardiorespiratory polygraphy including respiratory movements, nasal pressure flow, pulse oximetry, body position and motion.

MAIN OUTCOME MEASURES

Percentage of home cardiorespiratory studies successfully acquiring ≥4 hours of artefact-free data at the first attempt. Parental report of ease of use of equipment and preparedness to repeat home diagnostics in the future.

RESULTS

143/194 (74%; 95% CI 67% to 79%) of research participants and 50/61 (82%; 95% CI 71% to 90%) of clinical patients had successful home cardiorespiratory polygraphy at the first attempt. Some children required multiple attempts to achieve a successful study. Overall, this equated to 1.3 studies per research participant and 1.2 studies per clinical child. The median artefact-free sleep time for successful research studies was 515 min (range 261-673) and for clinical studies 442 min (range 291-583). 84% of research and 87% of clinical parents expressed willingness to repeat home cardiorespiratory polygraphy in the future. 67% of research parents found the equipment 'easy or okay' to use, while 64% of clinical parents reported it as 'easy' or 'very easy'.

CONCLUSIONS

Home cardiorespiratory polygraphy offers an acceptable approach to the assessment of sleep-disordered breathing in children.

摘要

目的

评估在家中进行心肺多导睡眠图检查(用于睡眠呼吸障碍研究)的成功率,以及家长对家用设备的看法。

设计

前瞻性观察研究。

地点

谢菲尔德、伊芙琳伦敦和南安普顿儿童医院。

患者

本研究共纳入了来自三个中心的 194 名研究参与者和一个中心的 61 名临床患者。所有参与者均患有唐氏综合征,年龄为 0.5-5.9 岁;61 名临床患者年龄为 0.4-19.5 岁,均接受了包括呼吸运动、鼻压气流、脉搏血氧饱和度、体位和运动在内的心肺多导睡眠图检查。

主要观察指标

首次尝试时成功获取≥4 小时无伪迹数据的家庭心肺多导睡眠图检查的百分比。家长对设备易用性的评价,以及对未来重复家庭诊断的准备情况。

结果

194 名研究参与者中,有 143 名(74%;95%置信区间为 67%至 79%)和 61 名临床患者中的 50 名(82%;95%置信区间为 71%至 90%)首次尝试即成功进行了家庭心肺多导睡眠图检查。一些患儿需要多次尝试才能成功完成检查。总体而言,这相当于每名研究参与者进行了 1.3 次研究,每名临床患儿进行了 1.2 次研究。成功的研究性研究中无伪迹的睡眠时间中位数为 515 分钟(范围为 261-673 分钟),临床研究中的无伪迹的睡眠时间中位数为 442 分钟(范围为 291-583 分钟)。84%的研究患儿家长表示愿意在未来重复进行家庭心肺多导睡眠图检查,87%的临床患儿家长表示愿意重复进行家庭心肺多导睡眠图检查。67%的研究患儿家长认为设备“容易或尚可”使用,而 64%的临床患儿家长认为设备“容易”或“非常容易”使用。

结论

在家中进行心肺多导睡眠图检查是评估儿童睡眠呼吸障碍的一种可接受的方法。

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