Shrestha Binaya, Dixit Sanjaya Mani
Department of Pharmacology, Kathmandu Medical College Teaching Hospital, Sinamangal, Kathmandu, Nepal.
J Nepal Health Res Counc. 2018 Oct 30;16(3):279-284.
In order to promote rational drug use in developing countries, assessment of drug use pattern using the World Health Organization drug use indicators is important. The aim of this study was to assess the drug prescription patterns at Kathmandu Medical College Teaching Hospital, using some of the World Health Organization core drug use indicators.
A prospective cross-sectional study was carried out in order to determine current prescribing trends at Kathmandu Medical College Teaching Hospital. A total of 605 prescriptions were collected and analyzed in the study.
The average number of drugs per prescription was 5.85 considering the total amount of prescriptions. Furthermore, assuming each prescription as an individual patient, 64.1% of patients received antibiotics, and 71% of patients received injectable form of drugs. Among antibiotics the most common antibiotics prescribed were Ceftriaxone, Amoxicillin/Cloxacillin, Azithromycin, Cefixime, and Cloxacillin. Only 16.94% of the medicines were prescribed in generic names with the rest 83.06% of the medicines being prescribed in brand names and 47.55% of medicines prescribed were from the National List of Essential Medicines-Nepal.
The current study revealed that polypharmacy and prescription writing using brand names were common. Prescriptions writing in generic name needs to be promoted and encouraged. There appears to be a crucial need for the development of prescribing guidelines when it comes to antibiotics.
为促进发展中国家合理用药,使用世界卫生组织药物使用指标评估用药模式很重要。本研究的目的是使用世界卫生组织一些核心药物使用指标评估加德满都医学院教学医院的药物处方模式。
开展一项前瞻性横断面研究,以确定加德满都医学院教学医院当前的处方趋势。本研究共收集并分析了605张处方。
考虑到处方总量,每张处方的平均药物数量为5.85种。此外,假设每张处方对应一名个体患者,64.1%的患者接受了抗生素治疗,71%的患者接受了注射剂型药物。在抗生素中,最常用的抗生素是头孢曲松、阿莫西林/氯唑西林、阿奇霉素、头孢克肟和氯唑西林。只有16.94%的药物以通用名开具,其余83.06%的药物以商品名开具,47.55%的处方药物来自尼泊尔基本药物清单。
当前研究表明,联合用药和使用商品名开具处方很常见。需要推广和鼓励使用通用名开具处方。在抗生素处方方面,似乎迫切需要制定处方指南。