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激素避孕药对睡眠的影响——绝经前女性失眠的一种可能治疗方法。

Effects of hormonal contraceptives on sleep - A possible treatment for insomnia in premenopausal women.

作者信息

Bezerra Andreia Gomes, Andersen Monica Levy, Pires Gabriel Natan, Tufik Sergio, Hachul Helena

机构信息

UNIFESP, Departamento de Psicobiologia - São Paulo - SP - Brasil.

Santa Casa de São Paulo School of Medical Sciences, Departamento de Ciências Fisiológicas - São Paulo - SP - Brasil.

出版信息

Sleep Sci. 2018 May-Jun;11(3):129-136. doi: 10.5935/1984-0063.20180025.

Abstract

Due to the changes that took place since the 1970s, women have achieved important socioeconomic positions. Many tasks, including domestic and familiar ones, continue to be under women's responsibility, which leads to an overload work. Additionally, the female organism has its peculiarities due to hormonal changes. Adding all these factors up, women seem to be more vulnerable to stressing factors and consequently, might be prone to present several health problems. Within this scenario, one can point out insomnia as a highly prevalent disease among women, directly affecting performance and quality of life. Progesterone has an important effect over sleep, acting both as a hypnogenic and as a respiratory stimulant. Hormonal contraceptives are largely recognized among the modern society women; however, little is known about the effects of these drugs on sleep. This proposal hypothesizes that the use of hormonal contraceptives, mainly those based on progestagens could be a new therapeutic element for the treatment of insomnia and one more tool to be used to improve women´s sleep pattern and quality of life.

摘要

自20世纪70年代以来,由于发生的种种变化,女性取得了重要的社会经济地位。许多任务,包括家务和家庭事务,仍由女性负责,这导致了工作负担过重。此外,由于荷尔蒙变化,女性机体有其独特之处。综合所有这些因素,女性似乎更容易受到压力因素的影响,因此可能更容易出现多种健康问题。在这种情况下,可以指出失眠是女性中一种非常普遍的疾病,直接影响工作表现和生活质量。孕酮对睡眠有重要影响,既是一种催眠剂,也是一种呼吸兴奋剂。激素避孕药在现代社会女性中广为人知;然而,人们对这些药物对睡眠的影响知之甚少。本提议假设,使用激素避孕药,主要是那些基于孕激素的避孕药,可能是治疗失眠的一种新的治疗手段,也是改善女性睡眠模式和生活质量的又一工具。

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