高原失代偿性心力衰竭患者的严重睡眠呼吸暂停、潮式呼吸及血氧饱和度下降

Severe sleep apnea, Cheyne-Stokes respiration and desaturation in patients with decompensated heart failure at high altitude.

作者信息

Vargas-Ramirez Leslie, Gonzalez-Garcia Mauricio, Franco-Reyes Camilo, Bazurto-Zapata Maria Angelica

机构信息

Fundacion Neumologica Colombiana, Sleep Center - Bogota - DC - Colômbia.

Fundacion Neumologica Colombiana, Research Department - Bogota - DC - Colombia.

出版信息

Sleep Sci. 2018 May-Jun;11(3):146-151. doi: 10.5935/1984-0063.20180028.

DOI:10.5935/1984-0063.20180028

PMID:30455846

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6201522/

Abstract

OBJECTIVES

To determine the sleep-disordered breathing in patients with decompensated HF (DHF) at an altitude of 2640m.

METHODS

Polysomnogram during the first 48 hours of admission in patients hospitalized for DHF. Sleep apnea (SA) was defined as an apnea hypopnea index (AHI) > 5/hour and central sleep apnea (CSA) as central apnea index (CAI) ≥ 50% of the AHI.

RESULTS

Sixteen participants, LVEF 24.2±9.9%. All patients had SA, severe in 12 (75%), CSA in 8 (50%) and 7 (43.8%) presented Cheyne-Stokes respiration (CSR). Out of the eight patients with obstructive SA, five had a central component (CAI ≥ 5/h). The SpO2 decreased during sleep to 80.6±5.5% and in patients with CSR to 77.6±6.9%.

CONCLUSIONS

At an altitude of 2640m all patients with DHF presented sleep apnea, most were severe, with CSA and a significant percentage of CSR that was associated with higher oxygen desaturation.

摘要

目的

确定海拔2640米处失代偿性心力衰竭（DHF）患者的睡眠呼吸障碍情况。

方法

对因DHF住院患者入院后48小时内进行多导睡眠图监测。睡眠呼吸暂停（SA）定义为呼吸暂停低通气指数（AHI）>5次/小时，中枢性睡眠呼吸暂停（CSA）定义为中枢性呼吸暂停指数（CAI）≥AHI的50%。

结果

16名参与者，左心室射血分数（LVEF）为24.2±9.9%。所有患者均有SA，其中12例（75%）为重度，8例（50%）有CSA，7例（43.8%）出现潮式呼吸（CSR）。在8例阻塞性SA患者中，5例有中枢性成分（CAI≥5次/小时）。睡眠期间血氧饱和度（SpO2）降至80.6±5.5%，CSR患者降至77.6±6.9%。