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经数字单操作孔胰管镜行电液碎石术治疗胰管结石(附视频)。

Electrohydraulic Lithotripsy for Pancreatic Duct Stones Under Digital Single-Operator Pancreatoscopy (with Video).

机构信息

2nd Department of Internal Medicine, Osaka Medical College, 2-7 Daigakuchou, Takatsukishi, Osaka, 569-8686, Japan.

出版信息

Dig Dis Sci. 2019 May;64(5):1377-1382. doi: 10.1007/s10620-018-5374-z. Epub 2018 Nov 19.

Abstract

BACKGROUND

Recently, a digital single-operator cholangiopancreatoscope (DSOC) has become available. This system allows the performance of electrohydraulic lithotripsy (EHL) even within the main pancreatic duct (MPD). However, there are only few reports of EHL for MPD stones using SPY-DS.

AIMS

The aim of this study was to evaluate the technical feasibility and efficacy of EHL for MPD stones under DSOC guidance.

METHODS

Between October 2016 and August 2017, patients with MPD stones were retrospectively enrolled in this study. The presence of MPD stones was diagnosed by endoscopic ultrasound and MRCP. The patients' baseline characteristics and those of the stones, including their size, number, and site in the MPD, number of EHL procedures, and adverse events, were reviewed.

RESULTS

A total of 21 patients were retrospectively enrolled. The etiologies of chronic pancreatitis were idiopathic (n = 4) and alcohol induced (n = 17). The pancreatic stone was variously located in the head (n = 6), body (n = 11), tail (n = 1), head and body (n = 2), and body and tail (n = 1) of the pancreas. Median pancreatic stone size was 12 mm, and the mean number of ERCP sessions was 1.29 (range 1-3). EHL was successfully performed in 15 patients (85.7%, 18/21), and the rate of complete stone clearance was 88.2% (18/21). Severe adverse events were not seen in any of the patients, although one patient developed mild acute pancreatitis.

CONCLUSIONS

In conclusion, although additional case reports and prospective studies are needed, EHL under DSOC may be an option to treat MPD stones.

摘要

背景

最近,一种数字单操作胆管胰管镜(DSOC)已经问世。该系统允许在主胰管(MPD)内进行电液压碎石术(EHL)。然而,使用 SPY-DS 进行 MPD 结石的 EHL 仅有少数报道。

目的

本研究旨在评估在 DSOC 引导下 EHL 治疗 MPD 结石的技术可行性和疗效。

方法

2016 年 10 月至 2017 年 8 月,回顾性纳入 MPD 结石患者。通过内镜超声和 MRCP 诊断 MPD 结石的存在。回顾患者的基线特征和结石特征,包括结石的大小、数量、位置、EHL 次数和不良事件。

结果

共回顾性纳入 21 例患者。慢性胰腺炎的病因包括特发性(n=4)和酒精性(n=17)。胰石位于胰头(n=6)、胰体(n=11)、胰尾(n=1)、胰头和胰体(n=2)、胰体和胰尾(n=1)。胰石中位数为 12mm,ERCP 次数的平均值为 1.29(范围 1-3)。15 例(85.7%,18/21)患者成功进行 EHL,结石完全清除率为 88.2%(18/21)。所有患者均未出现严重不良事件,仅 1 例发生轻度急性胰腺炎。

结论

尽管需要更多的病例报告和前瞻性研究,但在 DSOC 下进行 EHL 可能是治疗 MPD 结石的一种选择。

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