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[2018年欧洲心脏病学会妊娠期心血管疾病指南更新:最重要的要点]

[Update of the ESC guidelines 2018 on cardiovascular diseases during pregnancy : Most important facts].

作者信息

Seeland U, Bauersachs J, Roos-Hesselink J, Regitz-Zagrosek V

机构信息

Institut für Geschlechterforschung in der Medizin (GiM) und Center for Cardiovascular Research (CCR), Charité - Universitätsmedizin Berlin, Hessische Str. 3-4, 10115, Berlin, Deutschland.

DZHK (Deutsches Zentrum für Herz-Kreislauf-Forschung), Partnerseite Berlin, Berlin, Deutschland.

出版信息

Herz. 2018 Dec;43(8):710-718. doi: 10.1007/s00059-018-4765-4.

Abstract

Heart diseases are the most common cause of maternal death during pregnancy in Western countries. The current ESC guidelines 2018 for the management of cardiovascular diseases during pregnancy is a guide for any physician facing the challenge of caring for pregnant women with cardiovascular diseases. Among the new concepts compared to 2011, are recommendations to classify maternal risk due to the modified World Health Organization (mWHO) classification, introduction of the pregnancy heart team, guidance on assisted reproductive therapy, specific recommendations on anticoagulation for low-dose and high-dose requirements of vitamin K antagonists and the potential use of bromocriptine in peripartum cardiomyopathy. The Food and Drug Administration (FDA) categories A-D and X should no longer be used. Therefore, the table of drugs was completed with detailed information from animal and human studies on maternal and fetal risks. The new findings on specific heart diseases are presented in detail in the respective chapters.

摘要

在西方国家,心脏病是孕期孕产妇死亡的最常见原因。2018年欧洲心脏病学会(ESC)发布的妊娠期心血管疾病管理指南,为任何面临照顾患有心血管疾病孕妇挑战的医生提供了指导。与2011年相比的新概念包括:基于改良世界卫生组织(mWHO)分类法对孕产妇风险进行分类的建议、妊娠心脏团队的引入、辅助生殖治疗指南、针对维生素K拮抗剂低剂量和高剂量需求的抗凝具体建议以及溴隐亭在围产期心肌病中的潜在应用。美国食品药品监督管理局(FDA)的A-D和X类分类不应再使用。因此,药物表格补充了来自动物和人体研究的关于母婴风险的详细信息。各章节详细介绍了特定心脏病的新发现。

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