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局限性耐药性刺痛性白癜风对普瑞巴林的反应:一例报告。

Response of localized, resistant, tingling vitiligo to pregabalin: A case report.

机构信息

CUTIS Academy of Cutaneous Sciences, Bangalore, Karnataka, India.

出版信息

Dermatol Ther. 2018 Nov;31(6):e12702. doi: 10.1111/dth.12702. Epub 2018 Nov 19.

Abstract

Vitiligo is a common depigmenting disease with complex pathogenesis. One of the proposed pathogenesis is the neural hypothesis, which suggests an altered reaction to neuropeptides, catecholamines, and their metabolites affecting melanocytes. Here, we report a case of 26-year-old female patient, whose vitiligo patches were associated with unusual crawling and tingling sensation and responded to a clinical trial of pregabalin.

摘要

白癜风是一种常见的色素脱失性疾病,其发病机制复杂。其中一种提出的发病机制是神经假说,该假说表明对外源性神经肽、儿茶酚胺及其代谢物的反应改变,从而影响黑素细胞。在此,我们报告了一例 26 岁女性患者,其白癜风斑块伴有异常爬行感和刺痛感,并对普瑞巴林的临床试验有反应。

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