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白癜风:新出现的治疗方法

Vitiligo: new and emerging treatments.

作者信息

Lotti Torello, Gori Alessia, Zanieri Fabio, Colucci Roberta, Moretti Silvia

机构信息

Department of Dermatological Sciences, University of Florence, Florence, Italy.

出版信息

Dermatol Ther. 2008 Mar-Apr;21(2):110-7. doi: 10.1111/j.1529-8019.2008.00178.x.

DOI:10.1111/j.1529-8019.2008.00178.x
PMID:18394085
Abstract

Vitiligo is a cosmetically disfiguring condition, and, although there is no therapeutic full solution yet, some treatment may induce good results in most patients. The disease can be successfully treated with various medical options. Both nonfocused or focused narrowband ultraviolet B phototherapy represents the current treatment of choice, to minimize side effects and reach optimal clinical results. Topical novel approaches are also considered. Surgical methods, consisting of autologous transplantation methods, is generally recommended for focal/stable vitiligo, after medical therapy has failed. Finally, for patients with extensive vitiligo, depigmentation of the residual melanin should be taken into account.

摘要

白癜风是一种会导致容貌毁损的疾病,尽管目前尚无完全治愈的疗法,但一些治疗方法可使大多数患者获得较好疗效。该疾病可通过多种医学手段成功治疗。非聚焦或聚焦窄带紫外线B光疗是目前的首选治疗方法,可将副作用降至最低并取得最佳临床效果。新型局部治疗方法也在考虑之中。对于局限性/稳定期白癜风,在药物治疗失败后,通常推荐采用包括自体移植法在内的手术方法。最后,对于泛发性白癜风患者,应考虑对残留黑色素进行脱色素治疗。

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1
Vitiligo: new and emerging treatments.白癜风:新出现的治疗方法
Dermatol Ther. 2008 Mar-Apr;21(2):110-7. doi: 10.1111/j.1529-8019.2008.00178.x.
2
Combination of 308-nm xenon chloride excimer laser and topical calcipotriol in vitiligo.308纳米氯化氙准分子激光与外用卡泊三醇联合治疗白癜风。
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Topical calcipotriene and narrowband ultraviolet B in the treatment of vitiligo.外用卡泊三醇与窄谱中波紫外线治疗白癜风
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New and experimental treatments of vitiligo and other hypomelanoses.白癜风及其他色素减退症的新型和实验性治疗方法。
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Topical tacrolimus may enhance repigmentation with targeted narrowband ultraviolet B to treat vitiligo: a randomized, controlled study.外用他克莫司联合靶向窄谱中波紫外线可增强白癜风复色:一项随机对照研究
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Narrow-band ultraviolet B as monotherapy and in combination with topical calcipotriol in the treatment of vitiligo.窄谱中波紫外线光疗单药治疗及联合外用卡泊三醇治疗白癜风。
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A rational approach to the treatment of vitiligo and other hypomelanoses.白癜风及其他色素减退症的合理治疗方法。
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Update on skin repigmentation therapies in vitiligo.白癜风皮肤复色疗法的最新进展。
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Glycyrrhizin protects human melanocytes from H2O2‑induced oxidative damage via the Nrf2‑dependent induction of HO‑1.甘草酸通过 Nrf2 依赖性诱导 HO-1 保护人黑素细胞免受 H2O2 诱导的氧化损伤。
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