Sarrión-Sos Nerea, Morell-García Marta, Martínez-Sebastián Laura, Centeno-Rubiano José M, Montesinos-Sanchis Elena, Orta-Sibú Nelson
Servicio de Pediatría, Hospital General Universitario, Valencia, España.
Universidad de Carabobo, Valencia, Venezuela; Hospital General Universitario, Valencia, España.
Arch Argent Pediatr. 2018 Dec 1;116(6):e769-e772. doi: 10.5546/aap.2018.e769.
Septicemia is the main cause of neonatal mortality. The early-onset neonatal sepsis is usually related to maternal factor risks including recto-vaginal colonization. In the late-onset neonatal septicemia it is more difficult to establish the etiology because the majority of the cases are nosocomial or community related. The Streptococcus agalactiae (beta-hemolytic Streptococcus) is the most frequent germ associated with neonatal sepsis in developed countries. The late-onset form usually occurs with septic symptoms and meningitis and, in a few cases, with osteoarticular, skin and soft tissue infection. Adenitis-cellulitis syndrome is rarely seen, and its main cause is Staphylococcus aureus, followed by Streptococcus agalactiae. We report two cases of group B Streptococcus late-onset neonatal septicemia, both of them with adenitis-cellulitis syndrome. Patients recovered uneventfully after an adequate antibiotic therapy.
败血症是新生儿死亡的主要原因。早发型新生儿败血症通常与包括直肠阴道定植在内的母体因素风险有关。在晚发型新生儿败血症中，确定病因更为困难，因为大多数病例与医院或社区相关。无乳链球菌（β溶血性链球菌）是发达国家与新生儿败血症相关的最常见病菌。晚发型通常表现为败血症症状和脑膜炎，少数情况下表现为骨关节、皮肤和软组织感染。腺炎-蜂窝织炎综合征很少见，其主要病因是金黄色葡萄球菌，其次是无乳链球菌。我们报告了两例B组链球菌晚发型新生儿败血症病例，均伴有腺炎-蜂窝织炎综合征。经过适当的抗生素治疗后，患者顺利康复。
