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小儿外科多次麻醉病例报告:6年内80次麻醉应用

A case report of multiple anesthesia for pediatric surgery: 80 anesthesia applications in a period of 6 years.

作者信息

Oba Sibel, Türk Hacer Şebnem

机构信息

Şişli Hamidiye Etfal Education and Research Hospital, Anesthesiology and Reanimation Department Halaskargazi Cad. Etfal Sok, Istanbul, Şişli, Turkey.

出版信息

BMC Anesthesiol. 2018 Nov 20;18(1):175. doi: 10.1186/s12871-018-0639-9.

Abstract

BACKGROUND

The side and adverse effects of anesthesia and its neurotoxicity to children have become major concerns of anesthesiologists in recent years. Currently, no clinical trials have provided clear evidence indicating the suitable minimum age for a patient's first anesthetic application, importance of anesthesia duration, number of anesthetic applications or interval between two consecutive anesthesia applications. A very rare case concerning the side, adverse and neurotoxic effects of multiple anesthesia in a child is presented.

CASE PRESENTATION

A case of a 9-year-old child who received 80 applications of anesthesia in 6 years because of corrosive esophagitis is presented. The commonly used anesthetic agents were propofol, fentanyl, rocuronium and sevoflurane.

CONCLUSION

In our case, there were no permanent side or adverse effects due to multiple anesthesia. The minimal psychological and scholastic problems of our case were tied to frequent hospitalization by the pediatric psychiatry consultation.

摘要

背景

近年来,麻醉的副作用及其对儿童的神经毒性已成为麻醉医生主要关注的问题。目前,尚无临床试验提供明确证据表明患者首次应用麻醉的合适最低年龄、麻醉持续时间的重要性、麻醉应用次数或两次连续麻醉应用之间的间隔时间。本文报告了一例关于儿童多次麻醉的副作用、不良反应和神经毒性的极为罕见的病例。

病例介绍

本文介绍了一名9岁儿童的病例,该儿童因腐蚀性食管炎在6年内接受了80次麻醉。常用的麻醉剂有丙泊酚、芬太尼、罗库溴铵和七氟醚。

结论

在我们的病例中,多次麻醉未导致永久性的副作用或不良反应。我们病例中最小的心理和学业问题与儿科精神科会诊导致的频繁住院有关。

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本文引用的文献

1
Neurotoxicity of propofol on rat hypoglossal motoneurons in vitro.丙泊酚对大鼠舌下运动神经元的体外神经毒性
Neurosci Lett. 2017 Aug 10;655:95-100. doi: 10.1016/j.neulet.2017.06.040. Epub 2017 Jul 1.
4
Summary of the Update Session on Clinical Neurotoxicity Studies.临床神经毒性研究更新会议总结
J Neurosurg Anesthesiol. 2016 Oct;28(4):356-360. doi: 10.1097/ANA.0000000000000347.
10
Anesthetic neurotoxicity: what to tell the parents?麻醉神经毒性:该如何告知家长?
Paediatr Anaesth. 2014 Jan;24(1):120-6. doi: 10.1111/pan.12325. Epub 2013 Nov 27.

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