Laghari Altaf Ali, Bari Muhammad Ehsan, Waqas Muhammad, Ahmed Syed Ijlal, Nathani Karim Rizwan, Moazzam Wardah
Section of Neurosurgery, Aga Khan University Hospital, Karachi, Pakistan.
Department of neurosurgery, The Aga Khan University Hospital, Karachi, Pakistan.
Asian J Neurosurg. 2018 Oct-Dec;13(4):1053-1056. doi: 10.4103/ajns.AJNS_195_17.
The aim of the current study was to observe functional outcomes of patients undergoing decompressive craniectomy (DC) for raised intracranial pressure (ICP) after blunt head injury and to assess possible predictive factors.
This study was a prospective cohort study which was conducted at Aga Khan University Hospital, Karachi over a period of 2 years (January 2015-December 2016). Adult patients, aged between 15 and 65 years of both genders undergoing DC during the study period were selected. Outcomes of DC were assessed at an interval of 3 months following injury using the Glasgow outcome score. The data were analyzed on IBM statistics SPSS version 21.
Seventy-two patients underwent DC for raised and refractory ICP. Glasgow Outcome Scale (GOS) at discharge, 1-month and 3-month follow-up were reported. GOS at 3-month follow-up showed 21 patients (29.2%) patients had a good recovery, moderate disability was reported in 16 patients (22.2%), and severe disability in 12 patients (16.7%), persistent vegetative state was seen in five patients (6.9%). Eighteen patients had in hospital mortality (25.0%). Tracheostomy and sphenoid fractures were found to be negative predictors of good functional outcome.
DC is associated with an in hospital mortality of 25.0%. Favorable outcomes were seen in 51.4% patients. Tracheostomy and sphenoid fractures were negative predictors of good functional outcome. The results are comparable to international literature.
本研究旨在观察因钝性头部损伤导致颅内压(ICP)升高而接受减压颅骨切除术(DC)的患者的功能结局,并评估可能的预测因素。
本研究为前瞻性队列研究,在卡拉奇的阿迦汗大学医院进行,为期2年(2015年1月至2016年12月)。选取研究期间年龄在15至65岁之间、接受DC手术的成年患者。在受伤后每隔3个月使用格拉斯哥结局评分评估DC的结局。数据在IBM统计软件SPSS 21版上进行分析。
72例患者因ICP升高且难治而接受了DC手术。报告了出院时、1个月和3个月随访时的格拉斯哥结局量表(GOS)。3个月随访时的GOS显示,21例患者(29.2%)恢复良好,16例患者(22.2%)报告有中度残疾,12例患者(16.7%)有重度残疾,5例患者(6.9%)处于持续性植物状态。18例患者在医院死亡(25.0%)。气管切开术和蝶骨骨折被发现是良好功能结局的负性预测因素。
DC与25.0%的医院死亡率相关。51.4%的患者有良好结局。气管切开术和蝶骨骨折是良好功能结局的负性预测因素。结果与国际文献相当。