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血管中心性胶质瘤:1例以精神病为表现的罕见病例报告。

Angiocentric Glioma: Report of a Rare Case Presenting with Psychosis.

作者信息

Chaudhari Jayashri Popat, Kothari Kanchan Snehal, Pandya Tejal Pratin, Goel Naina Atul

机构信息

Department of Pathology, Seth G.S. Medical College and KEM Hospital, Mumbai, Maharashtra, India.

出版信息

Asian J Neurosurg. 2018 Oct-Dec;13(4):1186-1192. doi: 10.4103/ajns.AJNS_371_16.

Abstract

Angiocentric glioma (AG), first described in 2005, was included as a distinct entity in the 2007 World Health Organization Classification of Tumors of the Central Nervous System. It is a very rare cerebrocortical tumor mainly affecting children and young adults with a history of intractable partial seizures. The histopathological features of this entity are perivascular arrangement of monomorphic, bipolar spindled cells with subpial aggregation of tumor cells and variable neuroparenchymal colonization. Of uncertain histogenesis, this is a stable/slowly growing tumor. Prognosis following total surgical resection is favorable. We describe an AG in a 16-year-old, intellectually disabled, male patient, with psychosis. This is a rare presentation with only one such case in literature. Patient's symptoms ameliorated following surgery.

摘要

血管中心性胶质瘤(AG)于2005年首次被描述,并在2007年世界卫生组织中枢神经系统肿瘤分类中被列为一种独特的实体。它是一种非常罕见的脑皮质肿瘤,主要影响有顽固性部分性癫痫病史的儿童和年轻人。该实体的组织病理学特征是单形性双极梭形细胞围绕血管排列,肿瘤细胞在软膜下聚集,并伴有不同程度的神经实质浸润。其组织发生尚不明确,是一种稳定/生长缓慢的肿瘤。手术全切后的预后良好。我们描述了一名16岁、智力残疾、患有精神病的男性患者的血管中心性胶质瘤。这是一种罕见的表现,文献中仅有一例。患者术后症状有所改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1dd3/6208224/b7f8d7e62683/AJNS-13-1186-g001.jpg

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