Marcon Magda, Cereser Lorenzo, Girometti Rossano, Cataldi Palmina, Volpetti Stefano, Bazzocchi Massimo
Department of Medical and Biological Sciences, Institute of Diagnostic Radiology, University of Udine, University Hospital "Santa Maria della Misericordia", Udine, Italy.
Department of Medical and Morphological Sciences, University of Udine, University Hospital "Santa Maria della Misericordia", Udine, Italy.
BJR Case Rep. 2016 May 8;2(3):20150013. doi: 10.1259/bjrcr.20150013. eCollection 2016.
Extramedullary myeloma refers to the infiltration of neoplastic monoclonal plasma cells in either organs or soft tissues. The disease is clinically and radiologically underestimated compared with the autopsy findings and is usually associated with a more aggressive clinical course and poorer outcome. A minority of patients with extramedullary myeloma show hepatic involvement, usually in the form of diffuse parenchymal infiltration. When focal infiltration is present, variable imaging findings have been described both on CT scan and MRI. We report the case of a 63-year-old male with hepatitis B virus-related liver disease and biopsy-proven multiple myeloma involving the liver, manifesting as hypervascular focal liver lesions on MRI. A brief review of the literature is also proposed.
髓外骨髓瘤是指肿瘤性单克隆浆细胞浸润于器官或软组织。与尸检结果相比，该疾病在临床和影像学上常被低估，通常伴有更具侵袭性的临床病程和更差的预后。少数髓外骨髓瘤患者有肝脏受累，通常表现为弥漫性实质浸润。当存在局灶性浸润时，CT扫描和MRI上均有多种影像学表现。我们报告1例63岁男性患者，患有乙型肝炎病毒相关肝病，经活检证实为累及肝脏的多发性骨髓瘤，MRI表现为肝脏高血供局灶性病变。同时还对相关文献进行简要综述。
