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由神经囊尾蚴病引起的缺血性中风,表现为临床和影像学上的难题。

Ischaemic stroke induced by neurocysticerosis, presenting as a clinical and radiological dilemma.

作者信息

Hasan Rabia, Iaia Alberto, Flores Carlos

机构信息

Department of Radiology, Christiana Care Health System, Newark, DE, USA.

出版信息

BJR Case Rep. 2016 Jul 28;2(3):20150254. doi: 10.1259/bjrcr.20150254. eCollection 2016.

Abstract

Neurocysticercosis (NCC) is a central nervous system parasitic infection with various clinical presentations, rarely manifesting as an acute stroke. The radiological appearance of this disease entity may be non-specific, at times mimicking an intracranial neoplasm. Early diagnosis requires a high index of suspicion. Serological testing is helpful and, if utilized early, can reduce the morbidity associated with invasive diagnostic techniques. We describe a case of a 32-year-old previously healthy male who presented with neurological deficits. A cystic lesion in the right sylvian cistern was noted, initially identified as a benign arachnoid cyst. The patient's symptoms rapidly progressed to an acute stroke. Follow-up imaging including an MRI of the brain demonstrated a right middle cerebral artery territory infarct adjacent to the cystic lesion, which had been diagnosed as an arachnoid cyst on an initial CT scan. Appearance of the cystic lesion on MRI, however, was concerning for a brain neoplasm or an abscess. Given the contiguity of the cystic mass to the right middle cerebral artery, it was suggested that the mass was the likely aetiology of the patient's symptoms. A stereotactic biopsy of the cystic lesion was performed and revealed it to be NCC. The hospital course was complicated by intracranial hypertension and cerebral oedema requiring craniectomy. Our case highlights the importance of considering NCC in the differential diagnosis of stroke in patients coming from endemic regions, especially in younger patients lacking the usual risk factors for cerebrovascular disease.

摘要

神经囊尾蚴病(NCC)是一种中枢神经系统寄生虫感染,临床表现多样,很少表现为急性卒中。这种疾病实体的影像学表现可能不具有特异性,有时会模仿颅内肿瘤。早期诊断需要高度的怀疑指数。血清学检测很有帮助,如果早期使用,可以降低与侵入性诊断技术相关的发病率。我们描述了一例32岁以前健康的男性患者,他出现了神经功能缺损。在右侧外侧裂池发现一个囊性病变,最初被诊断为良性蛛网膜囊肿。患者的症状迅速发展为急性卒中。包括脑部MRI在内的后续影像学检查显示,在囊性病变附近有一个右侧大脑中动脉区域梗死灶,该囊性病变在最初的CT扫描中被诊断为蛛网膜囊肿。然而,MRI上囊性病变的表现令人怀疑是脑肿瘤或脓肿。鉴于囊性肿块与右侧大脑中动脉相邻,提示该肿块可能是患者症状的病因。对囊性病变进行了立体定向活检,结果显示为神经囊尾蚴病。患者的住院过程因颅内高压和脑水肿而复杂化,需要进行颅骨切除术。我们的病例强调了在来自流行地区的患者,尤其是缺乏常见脑血管疾病危险因素的年轻患者的卒中鉴别诊断中考虑神经囊尾蚴病的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e289/6243351/916e43c08de9/bjrcr.20150254.g001.jpg

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