Soejitno Andreas, Niryana I Wayan, Sriwidyani Ni Putu, Susilawathi Ni Made, Witari Ni Putu, Sudewi A A Raka
Departement of Neurology, Faculty of Medicine, Udayana University/Sanglah Hospital, Bali, Indonesia.
Departement of Neurosurgery, Faculty of Medicine, Udayana University/Sanglah Hospital, Bali, Indonesia.
IDCases. 2020 Nov 2;22:e01004. doi: 10.1016/j.idcr.2020.e01004. eCollection 2020.
Neurocysticercosis (NCC) is an infection of the central nervous system by the larval stage of pork tapeworm (). Diagnosing NCC can be challenging, particularly among those who reside in areas with rare occurrence of NCC and atypical manifestation such as a solitary parenchymal lesion. We treated a patient whose initially was diagnosed with brain abcess and later, brain tumor, only finally revealed to be an NCC case.
A 25-year old male suffered from multiple focal-to-bilateral tonic clonic seizures, was initially diagnosed as brain abscess. He was given antibiotics and anti-seizure medication but the seizure relapsed with a typical semiology. Physical examination demonstrated grade I papilledema, grade 4+ hemiparesis, and headache of vascular origin. Patient was suspected to have oligodendroglioma after underwent head MRI examination and subsequent tumor resection was performed. Pathological anatomy evaluation demonstrated multiple cystic segments containing larva of tapeworm, supporting a diagnosis of active NCC infection. After 14-day course of antheminthic treatment and resumed AED, patient was seizure-free and NCC was not found upon follow-up CT scan.
NCC, with respect to clinical and radiological manifestations, can be protean. A high index of suspicion towards NCC should always be maintained, particularly among patients originated from endemic area. Appropriate treatment with anthelminthic may result in full disease resolution, thus precluding unnecessary invasive approach.
神经囊尾蚴病(NCC)是由猪带绦虫幼虫阶段感染中枢神经系统所致。诊断NCC可能具有挑战性,尤其是在那些居住于NCC罕见地区且有非典型表现(如孤立性实质病变)的人群中。我们治疗了一名患者,其最初被诊断为脑脓肿,后来又被诊断为脑肿瘤,最终才确诊为NCC病例。
一名25岁男性患有多次局灶性至双侧强直阵挛性发作,最初被诊断为脑脓肿。给予了抗生素和抗癫痫药物,但癫痫发作仍以典型的发作形式复发。体格检查显示有I级视乳头水肿、4级以上偏瘫以及血管性头痛。患者在接受头部MRI检查后被怀疑患有少突胶质细胞瘤,随后进行了肿瘤切除。病理解剖评估显示多个含有绦虫幼虫的囊性节段,支持活动性NCC感染的诊断。经过14天的驱虫治疗疗程并恢复抗癫痫药物治疗后,患者无癫痫发作,随访CT扫描未发现NCC。
就临床和影像学表现而言,NCC可能多种多样。对于NCC应始终保持高度怀疑,尤其是在来自流行地区的患者中。适当的驱虫治疗可能会使疾病完全缓解,从而避免不必要的侵入性治疗方法。