Steffan P, Olaechea F, Roepstorff A, Bjorn H, Nansen P
Institute of Hygiene and Microbiology, Royal Veterinary and Agricultural University, Frederiksberg c, Denmark.
Vet Rec. 1988 Jul 30;123(5):128-30. doi: 10.1136/vr.123.5.128.
A controlled trial was performed to evaluate the efficacy of piperazine dihydrochloride in a new granular formulation (Ascarex D) against naturally occurring infections with Ascaris suum, Oesophagostomum dentatum and O quadrispinulatum. Treatment effects were estimated on the basis of parasites recoverable from the intestinal contents. Given orally at 200 mg per kg body weight the compound showed an efficacy of 99 to 100 per cent against A suum and the nodular worms. Egg excretion of the respective species was reduced by 98 per cent and 100 per cent six days after treatment. No adverse reactions were observed after the treatment.
进行了一项对照试验，以评估新颗粒制剂（Ascarex D）中的二盐酸哌嗪对自然发生的猪蛔虫、有齿食道口线虫和四棘食道口线虫感染的疗效。根据从肠道内容物中可回收的寄生虫来评估治疗效果。该化合物以每公斤体重200毫克的剂量口服给药时，对猪蛔虫和结节线虫的疗效为99%至100%。治疗六天后，各物种的虫卵排泄量分别减少了98%和100%。治疗后未观察到不良反应。
