State Key Laboratory of Photocatalysis on Energy and Environment, College of Chemistry, Fuzhou University, Fuzhou 350108, China.
Org Biomol Chem. 2018 Dec 5;16(47):9269-9273. doi: 10.1039/c8ob02647e.
A simple and efficient protocol for the copper-catalyzed synthesis of aryl or alkyl 2,2,2-trifluoroethyl selenoethers has been developed. This reaction proceeded smoothly in the presence of CuI/phen as the catalyst, with elemental selenium, 1,1,1-trifluoro-2-iodoethane, and NaBH4 as reagents in DMF with a broad scope of functionalized (hetero)aryl or alkyl halides. Different functional groups were tolerated and moderate to excellent yields of 2,2,2-trifluoroethyl selenoethers were obtained. Some of the synthesized compounds exhibited promising insecticidal activities.
一种简单高效的铜催化合成芳基或烷基 2,2,2-三氟乙基硒醚的方法已经被开发出来。在 CuI/苯并咪唑作为催化剂，元素硒、1,1,1-三氟-2-碘乙烷和 NaBH4 作为试剂，在 DMF 中反应，该反应可以顺利进行，具有广泛的官能化（杂）芳基或烷基卤化物的反应范围。不同的官能团被容忍，并且可以获得中等至优异的 2,2,2-三氟乙基硒醚产率。一些合成的化合物表现出有希望的杀虫活性。
