a Medical School, University of Cyprus , Nicosia , Cyprus.
Curr Med Res Opin. 2019 Jun;35(6):1027-1031. doi: 10.1080/03007995.2018.1552044. Epub 2018 Dec 21.
Adherence to allergen immunotherapy (AIT) is crucial for its efficacy. Subcutaneous AIT requires monthly visits (or more extended in the case of venom immunotherapy), while sublingual AIT is performed with a daily intake of allergen drops. Non-adherence to an AIT schedule and premature discontinuation are common problems. Various studies have shown controversial results on the rate of AIT adherence. The aim of this review is to describe the problem of non-adherence and to offer some evidence-based advice to allergologists on how to increase it. Better patient education at the beginning of treatment, sharing with patients the decision on which type of immunotherapy to select and showing sincere interest in their treatment concerns are some tips that can help to increase adherence. A well organized allergologist time schedule not only increases safety but also offers the possibility of close follow-up and an increase in patient loyalty.
变应原免疫治疗（AIT）的依从性对于其疗效至关重要。皮下免疫治疗需要每月就诊（在毒液免疫治疗的情况下可能会延长），而舌下免疫治疗则需要每天摄入过敏原滴剂。不遵守 AIT 计划和过早停药是常见的问题。多项研究对 AIT 依从率的结果存在争议。本综述旨在描述不依从的问题，并为过敏学家提供一些循证建议，以提高依从性。在治疗开始时进行更好的患者教育，与患者共同决定选择哪种类型的免疫治疗，并真诚关注他们的治疗问题，这些都是可以帮助提高依从性的建议。合理安排过敏科医生的时间安排不仅可以提高安全性，还可以提供密切随访和增加患者忠诚度的可能性。
