Lanza Fernanda C, Castro Rejane A S, de Camargo Anderson A, Zanatta Drielly J M, Rached Samia, Athanazio Rodrigo, Cukier Alberto, Stelmach Rafael, Dal Corso Simone
a Postgraduate Program in Rehabilitation Sciences , Universidade Nove de Julho - UNINOVE , São Paulo , Brazil.
b Pulmonary Division, Heart Institute (InCor) , Faculdade de Medicina da Universidade de São Paulo , São Paulo , Brazil.
COPD. 2018 Oct;15(5):512-519. doi: 10.1080/15412555.2018.1540034. Epub 2018 Nov 23.
The COPD assessment test (CAT) is a short questionnaire developed to help patients and clinicians to assess the impact of symptoms in routine clinical practice. We aimed to validate and to test the reproducibility of CAT in patients with bronchiectasis and correlate with the severity of dyspnea, aerobic and functional capacity, and physical activity in daily life. This is a cross-sectional study, patients with bronchiectasis underwent spirometry, cardiopulmonary exercise test (CPET), incremental shuttle walk test (ISWT), Saint George`s Respiratory Questionnaire (SGRQ), and received pedometer. CAT was applied twice (CAT-1 and CAT-2, 7 to 10 days apart). The severity of bronchiectasis was assessed by E-FACED and bronchiectasis severity index (BSI). A total of 100 patients were evaluated (48 ± 14 years, 59 women, FVC: 67 ± 22% pred, FEV: 52 ± 25% pred). According to CAT, 14% patients presented low, 40% medium, 32% high, and 14% very high impact. The higher the CAT, the worse the severity of bronchiectasis, dyspnea, quality of life, performance on the CPET, and smaller the distance walked (DW) on the ISWT and number of steps (NS) per day. There was significant correlation between CAT and SGRQ, E-FACED, BSI, NS, ISWT, oxygen uptake, and workload at CPET. CAT-1 and CAT-2 presented similar values: 21 (13-26) and 19 (13-26), respectively. The CAT is a valid and reproducible instrument in patients with bronchiectasis presenting good correlation with clinical, functional, and quality of life measurements. This easy-to-use, easy-to-understand, quick, and useful tool may play an important role to assess the impact of bronchiectasis on both daily medical practice and clinical trial settings.
慢性阻塞性肺疾病评估测试（CAT）是一份简短问卷，旨在帮助患者和临床医生在日常临床实践中评估症状的影响。我们旨在验证并测试CAT在支气管扩张症患者中的可重复性，并将其与呼吸困难的严重程度、有氧运动和功能能力以及日常生活中的身体活动相关联。这是一项横断面研究，支气管扩张症患者接受了肺活量测定、心肺运动试验（CPET）、递增往返步行试验（ISWT）、圣乔治呼吸问卷（SGRQ），并佩戴了计步器。CAT进行了两次测试（CAT - 1和CAT - 2，间隔7至10天）。通过E - FACED和支气管扩张严重指数（BSI）评估支气管扩张的严重程度。共评估了100名患者（48±14岁，59名女性，FVC：67±22%预计值，FEV：52±25%预计值）。根据CAT评估，14%的患者影响程度低，40%为中度，32%为高度，14%为非常高。CAT越高，支气管扩张的严重程度、呼吸困难、生活质量、CPET表现越差，ISWT中的步行距离（DW）和每天的步数（NS）越少。CAT与SGRQ、E - FACED、BSI、NS、ISWT、摄氧量以及CPET时的工作量之间存在显著相关性。CAT - 1和CAT - 2呈现出相似的值：分别为21（13 - 26）和19（13 - 26）。CAT是一种有效且可重复的工具，在支气管扩张症患者中与临床、功能和生活质量测量具有良好的相关性。这个易于使用、易于理解、快速且有用的工具可能在评估支气管扩张症对日常医疗实践和临床试验环境的影响方面发挥重要作用。
