四氧嘧啶：历史与作用机制 - Suppr

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超能文献

Alloxan: history and mechanism of action.

作者信息

Lenzen S, Panten U

机构信息

Institute of Pharmacology and Toxicology, University of Göttingen, FRG.

出版信息

Diabetologia. 1988 Jun;31(6):337-42. doi: 10.1007/BF02341500.

DOI:10.1007/BF02341500

PMID:3046975

Abstract

摘要

相似文献

Alloxan: history and mechanism of action.四氧嘧啶：历史与作用机制

Diabetologia. 1988 Jun;31(6):337-42. doi: 10.1007/BF02341500.

Concanavalin A and alloxan interactions on glucose-induced insulin secretion and biosynthesis from islets of Langerhans.伴刀豆球蛋白A与四氧嘧啶对葡萄糖诱导的胰岛胰岛素分泌及生物合成的相互作用。

Diabetes. 1984 Feb;33(2):164-9. doi: 10.2337/diab.33.2.164.

Molecular target structures in alloxan-induced diabetes in mice.小鼠中四氧嘧啶诱导糖尿病的分子靶标结构

Life Sci. 2002 Aug 23;71(14):1681-94. doi: 10.1016/s0024-3205(02)01918-5.

Identification of glucokinase as an alloxan-sensitive glucose sensor of the pancreatic beta-cell.鉴定葡萄糖激酶为胰腺β细胞的一种对四氧嘧啶敏感的葡萄糖传感器。

Diabetes. 1986 Oct;35(10):1163-73. doi: 10.2337/diab.35.10.1163.

Effect of alloxan administration on the blood glucose, pancreatic islets and the glycogen in some tissues of Clarias batrachus (Linn.).四氧嘧啶给药对胡子鲶（Clarias batrachus (Linn.)）血糖、胰岛及某些组织中糖原的影响。

Z Mikrosk Anat Forsch. 1974;88(3):567-75.

DNA strand breaks in pancreatic islets by in vivo administration of alloxan or streptozotocin.

Biochem Biophys Res Commun. 1981 Dec 15;103(3):1014-20. doi: 10.1016/0006-291x(81)90910-4.

Differential target molecules for toxicity induced by streptozotocin and alloxan in pancreatic islets of mice in vitro.链脲佐菌素和四氧嘧啶体外诱导小鼠胰岛毒性的差异靶分子

Exp Clin Endocrinol Diabetes. 2004 Jan;112(1):29-37. doi: 10.1055/s-2004-815724.

Effect of metabolic alkalosis on the B-cell sensitivity to alloxan in vivo.

Horm Metab Res. 1978 Nov;10(6):477-81. doi: 10.1055/s-0028-1093375.

[Glucokinase and insulin secretion].[葡萄糖激酶与胰岛素分泌]

Seikagaku. 1986 Dec;58(12):1483-8.

Alloxan-induced diabetes-evidence for hydroxyl radical as a cytotoxic intermediate.四氧嘧啶诱导的糖尿病——羟基自由基作为细胞毒性中间体的证据。

Biochem Pharmacol. 1976 May 1;25(9):1085-92. doi: 10.1016/0006-2952(76)90502-5.

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Evaluation of Safety of Stewart's Wood Fern () and Its Anti-Hyperglycemic Potential in Alloxan-Induced Diabetic Mice.评价肾叶金粉蕨（Stewart's Wood Fern (Dryopteris stewartii)）的安全性及其在四氧嘧啶诱导的糖尿病小鼠中的降血糖潜力。

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A system-level approach to investigate alloxan-induced toxicity in microtubule-binding protein to lead type 2 diabetes mellitus.系统水平方法研究微管结合蛋白在导致 2 型糖尿病中的丙烯醛毒性。

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本文引用的文献

Protective effects of glutathione and cysteine against alloxan diabetes in the rat.谷胱甘肽和半胱氨酸对大鼠四氧嘧啶糖尿病的保护作用。

Proc Soc Exp Biol Med. 1946 Apr;61:441-7. doi: 10.3181/00379727-61-15347.

Further studies of effect of sulphur compounds on production of diabetes with aloxan.硫化合物对四氧嘧啶诱导糖尿病产生影响的进一步研究。

Proc Soc Exp Biol Med. 1947 Oct;66(1):4-7. doi: 10.3181/00379727-66-15963.

Alloxan Diabetes-Its Production and Mechanism.四氧嘧啶糖尿病——其产生及机制

Bull N Y Acad Med. 1945 Jan;21(1):44-55.

Alloxan diabetes.四氧嘧啶糖尿病

Physiol Rev. 1948 Jul;28(3):304-30. doi: 10.1152/physrev.1948.28.3.304.

Factors controlling the development and progression of diabetes.

Physiol Rev. 1949 Jan;29(1):48-74. doi: 10.1152/physrev.1949.29.1.48.

Inhibition of enzymatic transphosphorylation by alloxan and ninhydrin in tissue extracts.四氧嘧啶和茚三酮对组织提取物中酶促转磷酸化作用的抑制

Arch Biochem. 1949 Feb;20(2):451-6.

Alloxan and dialuric acid; their stabilities and ultraviolet absorption spectra.四氧嘧啶和双脲酸；它们的稳定性及紫外吸收光谱。

J Biol Chem. 1949 Jan;177(1):187-96.

The Mechanism of Cysteine and Glutathione Protection Against Alloxan Diabetes.半胱氨酸和谷胱甘肽对四氧嘧啶糖尿病的保护机制。

Science. 1948 Sep 17;108(2803):308-9. doi: 10.1126/science.108.2803.308.

Further observations on the effects of alloxan on the pancreatic islets.关于四氧嘧啶对胰岛作用的进一步观察

J Physiol. 1944 Sep 29;103(2):233-43. doi: 10.1113/jphysiol.1944.sp004072.

Reversal of the diabetogenic action of alloxan by sulfhydryl compounds.巯基化合物对四氧嘧啶致糖尿病作用的逆转

Science. 1952 Jan 11;115(2976):41-3. doi: 10.1126/science.115.2976.41.

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