Division of Urology, Department of Surgery, University of Utah, Salt Lake City, UT, USA.
Nat Rev Urol. 2019 Jan;16(1):54-64. doi: 10.1038/s41585-018-0122-x.
Renal trauma research has historically focused on parenchymal injuries and the risk of bleeding. However, much less is known about the diagnosis and optimal management of urinary extravasation, which complicates ~30% of high-grade renal injuries. Immediate or delayed ureteral stenting is the most common procedure used to treat collecting system injuries when intervention is needed. However, the lack of evidence-based guidelines leaves the diagnosis and management of urinary extravasation largely dependent upon physicians' experience, initial and follow-up imaging protocols, and the definitions used for grading the injuries. The knowledge gaps in the management of urinary extravasation that need to be addressed include the timing of excretory-phase CT imaging, patterns of clinically significant urinary extravasation, predictors of complications when urinary extravasation occurs, protocols for obtaining and interpreting follow-up imaging, and the role of ureteral stenting and other interventions in management. To improve the management of urinary extravasation after high-grade renal trauma, large, multi-institutional prospective trails assessing different diagnostic and therapeutic protocols are needed.
肾损伤研究历史上主要集中在实质损伤和出血风险上。然而,对于尿外渗的诊断和最佳治疗方法知之甚少,尿外渗约占 30%的高级别肾损伤。当需要干预时,立即或延迟输尿管支架置入术是最常用于治疗集合系统损伤的常见方法。然而,缺乏循证指南使得尿外渗的诊断和管理在很大程度上取决于医生的经验、初始和随访成像方案以及用于分级损伤的定义。需要解决的尿外渗管理知识空白包括排泄期 CT 成像的时间、临床上显著尿外渗的模式、尿外渗发生时并发症的预测因素、获取和解释随访成像的方案以及输尿管支架置入术和其他干预措施在管理中的作用。为了改善高级别肾损伤后尿外渗的管理,需要进行大型、多机构的前瞻性试验,评估不同的诊断和治疗方案。