Lu Zhi-Hua, Ji Li-Biao, Zhao Wen-Lu, Zhang Yong-Sheng, Wu Jiang-Fen, Li Xin, Shen Jun-Kang
Department of Radiology, the Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
Department of Pathology, the Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
J Comput Assist Tomogr. 2019 Mar/Apr;43(2):235-241. doi: 10.1097/RCT.0000000000000829.
To compare the diagnostic performance of standard and ultrahigh b-value Diffusion-weighted Imaging (DWI) using volumetric histogram analysis in differentiating transition zone (TZ) cancer from benign prostatic hyperplasia (BPH).
57 TZ cancer and 61 BPH patients received standard (1000 s/mm) and ultrahigh b-value (2000 s/mm) DWI. The diagnostic ability of ADC histogram parameters derived from two DWI for differentiating TZ cancer from BPH was determined by receiver operating characteristic curve.
Median, minimum, the 10th, 25th percentile ADC in both ADC1000 and ADC2000 and skewness in ADC2000 had significant differences between TZ cancer and BPH (for all, P < 0.05).The 10th percentile ADC showed highest area under the ROC curve (AUC) in both ADC1000 and ADC2000.The 10th percentile ADC of ADC2000 showed significantly higher AUC than did ADC1000 (P = 0.0385).
The 10th percentile ADC obtained from ultrahigh b-value DWI performed better for differentiating TZ cancer from BPH.
运用容积直方图分析比较标准b值和超高b值扩散加权成像（DWI）在鉴别移行区（TZ）癌与良性前列腺增生（BPH）方面的诊断性能。
57例TZ癌患者和61例BPH患者接受了标准b值（1000 s/mm²）和超高b值（2000 s/mm²）的DWI检查。通过受试者操作特征曲线确定两种DWI得出的ADC直方图参数在鉴别TZ癌与BPH方面的诊断能力。
TZ癌与BPH在ADC1000和ADC2000的中位数、最小值、第10百分位数、第25百分位数ADC以及ADC2000的偏度方面存在显著差异（均P < 0.05）。第10百分位数ADC在ADC1000和ADC2000中均显示出最高的ROC曲线下面积（AUC）。ADC2000的第10百分位数ADC显示出的AUC显著高于ADC1000（P = 0.0385）。
从超高b值DWI获得的第10百分位数ADC在鉴别TZ癌与BPH方面表现更佳。
