Touney Eric E, Foy Nicholas J, Pronin Sergey V
Department of Chemistry , University of California , Irvine , California 92697-2025 , United States.
J Am Chem Soc. 2018 Dec 12;140(49):16982-16987. doi: 10.1021/jacs.8b12075. Epub 2018 Nov 30.
Radical-polar crossover hydrofunctionalizations of tertiary allylic alcohols are described. Depending on the structure of the catalyst, corresponding epoxides or semipinacol rearrangement products are selectively obtained in good yields. Experimental evidence points to the participation of alkylcobalt complexes as electrophilic intermediates.
描述了叔烯丙醇的自由基-极性交叉氢官能化反应。根据催化剂的结构，可选择性地以良好产率得到相应的环氧化物或半频哪醇重排产物。实验证据表明烷基钴配合物作为亲电中间体参与反应。
