Meklenborg Ida, Pedersen Michael Lynge, Bonefeld-Jørgensen Eva Cecilie
a Department of Clinical Medicine , Aarhus University , Aarhus , Denmark.
b Greenland Center for Health Research, Institute of Nursing and Health Science , University of Greenland , Nuuk , Greenland.
Int J Circumpolar Health. 2018 Dec;77(1):1542930. doi: 10.1080/22423982.2018.1542930.
Diabetes mellitus is a large and growing worldwide health issue. Prior to this publication, a direct comparison of the prevalence of persons treated with anti-diabetic medicine in Greenland and Denmark has not been found. Therefore, the aim of this study is to estimate and compare the age- and gender-specific prevalence of patients treated with anti-diabetic medicine comparing Greenland and Denmark. The study was performed as a cross-sectional register study using data from population and medical registers in Greenland and Denmark. A total of 784 Greenlandic and 215,580 Danish patients treated with anti-diabetic medicine were included. The prevalence of patients aged 20-79 years treated with anti-diabetic medicine in Greenland was 2.6% (95% CI 2.4-2.8), much lower (p < 0.001) compared to Denmark with 5.2% (95% CI 5.2-5.2). The difference was less pronounced after excluding those treated with insulin and women below 45 years treated with metformin. In conclusion, this study showed a lower prevalence of patients treated with anti-diabetic medicine in Greenland than Denmark. The main reason may be a much higher prevalence of undiagnosed diabetes in Greenland, particularly among the middle-aged. Differences in awareness of diabetes and access to continued primary healthcare may be contributing factors.
糖尿病是一个在全球范围内规模庞大且不断增长的健康问题。在本出版物发表之前,尚未发现对格陵兰岛和丹麦接受抗糖尿病药物治疗的人群患病率进行直接比较的研究。因此,本研究的目的是估计并比较格陵兰岛和丹麦接受抗糖尿病药物治疗的患者按年龄和性别划分的患病率。该研究采用横断面登记研究方法,使用了格陵兰岛和丹麦的人口与医疗登记数据。共纳入了784名接受抗糖尿病药物治疗的格陵兰患者和215,580名丹麦患者。格陵兰岛20至79岁接受抗糖尿病药物治疗的患者患病率为2.6%(95%置信区间2.4 - 2.8),与丹麦的5.2%(95%置信区间5.2 - 5.2)相比要低得多(p < 0.001)。在排除接受胰岛素治疗的患者以及45岁以下接受二甲双胍治疗的女性后,差异不再那么明显。总之,本研究表明格陵兰岛接受抗糖尿病药物治疗的患者患病率低于丹麦。主要原因可能是格陵兰岛未确诊糖尿病的患病率要高得多,尤其是在中年人中。对糖尿病的认知差异以及获得持续初级医疗保健的机会可能是促成因素。