经皮神经电刺激治疗尼日利亚新伊比地区坐骨神经痛的非随机对照临床试验。

Effects of transcutaneous electrical nerve stimulation in the Management of Post-Injection Sciatic Pain in a non-randomized controlled clinical trial in Nnewi, Nigeria.

机构信息

Department of Physiotherapy, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Anambra State, PMB 5025, Nigeria.

Department of Medical Rehabilitation, Faculty of Health Sciences and Technology, University of Nigeria|, Enugu Campus, Enugu State, Nigeria.

出版信息

BMC Complement Altern Med. 2018 Nov 26;18(1):310. doi: 10.1186/s12906-018-2373-8.

DOI:10.1186/s12906-018-2373-8

PMID:30477485

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6258320/

Abstract

BACKGROUND

Many studies on transcutaneous electrical nerve stimulation (TENS) had been undertaken to explore its pain relieving efficiency on several medicals/surgical conditions but none, specifically, had been carried out to determine the effect it has on post-injection sciatic pain (PISP) which comes about from wrong administration of intramuscular pain. This study aims to assess the effects of TENS in the management of PISP.

METHODS

A total of 72 PISP subjects comprising 40 test subjects and 32 control subjects participated in a non-randomized controlled clinical trial in the current study. Participants were recruited from Department of Physiotherapy, Nnamdi Azikiwe University Teaching Hospital, Nnewi and Landmark Physiotherapy Services, Nnewi. The participants were however blinded to the intervention method they will receive before being allotted conveniently to test/experimental group (TG) or control group (CG). A written informed consent was obtained from participants before enrollments in the study. TENS and sham TENS (STENS) was applied to 40 test and 32 subjects respectively, 3 times a week, and 1 hour per session for the 10 weeks the study lasted. The Visual Analogue Scale was used to collect baseline data as well as those of 2nd, 4th, 6th, 8th and 10th weeks after TENS and STENS interventions. The data analysis was performed with the Descriptive statistic of Mean ± SD, mean comparison test, repeated analysis of variance and paired wise t-test. Statistical level of significance was set at P < 0.05.

RESULT

Results of repeated measure ANOVA showed that the pain level among participants in the treatment group at the end (after 10 weeks) of the intervention was significantly lower than that of their counterparts in the control group (F = 16.26; p = 0.01); with the intervention accounting for the 19% of the variance. The effect size (partial eta squared) = 0.19.

CONCLUSION

The outcome of this research has proved the effectiveness of TENS in the management of PISP and is being recommended in the management of PISP.

TRIAL REGISTRATION

Pan Africa Clinical Trial Registry ( PACTR201805003408271 ). The study was registered retrospectively on the 29th May, 2018.

摘要

背景

许多关于经皮神经电刺激（TENS）的研究都探讨了其在多种医学/外科疾病中的止痛效果，但没有专门研究 TENS 对因肌肉内疼痛注射错误引起的坐骨神经后注射痛（PISP）的影响。本研究旨在评估 TENS 在管理 PISP 中的效果。

方法

共有 72 名 PISP 受试者参加了本研究的非随机对照临床试验，其中 40 名试验组和 32 名对照组。参与者是从纳姆迪·阿齐克韦大学教学医院理疗科和里程碑理疗服务公司招募的。在分配到试验/实验组（TG）或对照组（CG）之前，参与者对他们将接受的干预方法并不知情。在研究开始前，所有参与者均签署了书面知情同意书。TENS 和假 TENS（STENS）分别应用于 40 名试验组和 32 名对照组，每周 3 次，每次 1 小时，共 10 周。在 TENS 和 STENS 干预后的第 2、4、6、8 和 10 周，使用视觉模拟评分法收集基线数据和其他数据。采用均值±标准差的描述性统计、均值比较检验、重复方差分析和配对 t 检验进行数据分析。显著性水平设为 P<0.05。