Fu Xiao-Yan, Xie Xiao-Tian
Department of Pediatrics, Shanghai Luodian Hospital, Shanghai 201908, China.
Zhongguo Dang Dai Er Ke Za Zhi. 2018 Nov;20(11):964-967. doi: 10.7499/j.issn.1008-8830.2018.11.017.
Iron deficiency (ID) is the most common trace element deficiency in childhood. Recent studies have shown that late fetus period, neonatal period, and infancy are important periods for brain development, and ID during these periods may cause irreversible damage to brain development, including abnormal emotion and behavior, cognitive decline, and attention deficit, which may still be present in adulthood. Therefore, it should be taken seriously. This article summarizes the research advances in major mechanisms involved in brain developmental disorder due to ID in the early stage of life and related intervention measures.
缺铁(ID)是儿童期最常见的微量元素缺乏症。最近的研究表明,胎儿后期、新生儿期和婴儿期是大脑发育的重要时期,这些时期的缺铁可能会对大脑发育造成不可逆转的损害,包括情绪和行为异常、认知能力下降以及注意力缺陷,这些问题在成年期可能仍然存在。因此,应予以重视。本文综述了生命早期缺铁所致脑发育障碍的主要机制及相关干预措施的研究进展。