Giroud M, Guard O, Dumas R
Service de Neurologie, C.H.U. de Dijon.
Rev Neurol (Paris). 1988;144(4):284-8.
A case of acute pulmonary edema without cardiac failure, infectious or toxic cause, revealing a Multiple Sclerosis (M.S.), one case of bradycardia during a bout in a known M.S. and one case of orthostatic hypotension without change of cardiac frequency, during a bout of a known M.S. are reported. The common point of these 3 cases is that during their autonomic failure, there were disorders pointing to the medulla oblongata: swallowing difficulties, rotatory nystagmus, vestibulo-cerebellar syndrome, sensory and motor defect of upper limbs. A plaque of M.S. in the medulla oblongata, particularly near the tractus solitarius could explain these cardio-pulmonary abnormalities unusual in M.S.
报告了1例无心力衰竭、感染或中毒原因的急性肺水肿病例，该病例为多发性硬化症（MS）的首发症状；1例已知患有MS的患者在发作期间出现心动过缓；1例已知患有MS的患者在发作期间出现体位性低血压，但心率无变化。这3例病例的共同点是，在自主神经功能衰竭期间，存在指向延髓的功能障碍：吞咽困难、旋转性眼球震颤、前庭小脑综合征、上肢感觉和运动缺陷。延髓，特别是孤束核附近的MS斑块，可以解释这些在MS中不常见的心肺异常。
