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铋:对胃炎和消化性溃疡的影响。

Bismuth: effects on gastritis and peptic ulcer.

作者信息

Rokkas T, Sladen G E

机构信息

Gastroenterology Unit, Guy's Hospital Medical School, London, UK.

出版信息

Scand J Gastroenterol Suppl. 1988;142:82-6. doi: 10.3109/00365528809091719.

DOI:10.3109/00365528809091719
PMID:3047853
Abstract

The healing properties of colloidal bismuth subcitrate (CBS) on peptic ulcer are well established and several studies have shown that healing with CBS is associated with a lower relapse rate than that produced by H2-receptor antagonists. The recent observation that CBS is effective against Campylobacter pylori has shed light on this because recent studies have shown that eradication of C. pylori by CBS leads to resolution of the associated gastritis and this may explain the low relapse rates. CBS is also effective in C. pylori positive patients with non ulcer dyspepsia (NUD) in whom clearance of these organisms from the stomach is associated with significant improvement of the associated gastritis and symptoms.

摘要

胶体次枸橼酸铋(CBS)对消化性溃疡的愈合特性已得到充分证实,多项研究表明,与H2受体拮抗剂相比,CBS治疗后的溃疡复发率更低。最近发现CBS对幽门螺杆菌有效,这为上述现象提供了解释,因为最近的研究表明,CBS根除幽门螺杆菌可使相关胃炎得到缓解,这可能是复发率低的原因。CBS对幽门螺杆菌阳性的非溃疡性消化不良(NUD)患者也有效,清除胃内这些细菌可使相关胃炎和症状得到显著改善。

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Bismuth: effects on gastritis and peptic ulcer.铋:对胃炎和消化性溃疡的影响。
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2
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2
Utilization of time-kill kinetic methodologies for assessing the bactericidal activities of ampicillin and bismuth, alone and in combination, against Helicobacter pylori in stationary and logarithmic growth phases.利用时间杀菌动力学方法评估氨苄青霉素和铋单独及联合使用对处于稳定期和对数生长期的幽门螺杆菌的杀菌活性。
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