Lutz F
Institut für Pharmakologie und Toxikologie im Fachbereich Veterinärmedizin, Justus-Liebig-Universität Giessen.
Tierarztl Prax. 1988;16(2):113-8.
The present paper summarizes the pharmacokinetics of chemotherapeutic agents commonly used in controlling bacterial disease in animals. Data on absorption, distribution and excretion of chemotherapeutic agents are given in form of tables. It is explained that pharmacokinetic parameters of antimicrobial chemotherapy among others are influenced by the drug's pharmaceutical formulation, its route of administration, its biotransformation and also by the age of the patients. There are given hints for handling the drug in order to achieve optimal effects.
本文总结了常用于控制动物细菌性疾病的化疗药物的药代动力学。化疗药物吸收、分布和排泄的数据以表格形式给出。文中解释了抗菌化疗的药代动力学参数等受到药物剂型、给药途径、生物转化以及患者年龄的影响。还给出了用药提示以达到最佳效果。