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冠状动脉充盈不足:冠状动脉手术后关于受体动脉质量和左心室功能的一些术前和术后观察

The underfilled coronary artery: some pre- and post-operative observations on recipient arterial quality and left ventricular function after coronary artery surgery.

作者信息

Partridge J B, Brandt P W, Whitlock R M

出版信息

Clin Radiol. 1978 Jan;29(1):5-8. doi: 10.1016/s0009-9260(78)80155-x.

Abstract

In a series of 141 saphenous vein aortocoronary bypass grafts in 59 patients undergoing routine restudy of the coronary arteries within four weeks of operation, an overall graft occlusion rate of 12% was found. A trend towards a higher occlusion rate was seen in arteries that were small (19%), that had a limited run-off (15%), significant distal disease (24%) or severe atheroma at the graft site (22%). Statistically, these occlusion rates are not significantly different from the overall failure rate and do not give absolute contra-indications to grafting. A particular group of arteries which seemed underfilled in the pre-operative angiogram (1.5 mm or less in diameter but apparently healthy with smooth walls and supplying a larger area of myocardium than would be expected from their apparent size) was identified. These arteries showed a significant increase in diameter in the post-operative angiograms and had a low occlusion rate (1 of 15 grafts; 7%). When all grafts were patent, the mean post-operative left ventricular ejection fraction showed a significant increase over the pre-operative valve, but when one or more grafts were occluded there was no significant change.

摘要

在对59例患者进行的141例大隐静脉主动脉冠状动脉旁路移植术中,这些患者在术后四周内接受了常规的冠状动脉复查,结果发现总的移植血管闭塞率为12%。在一些血管中可见闭塞率有升高趋势,这些血管包括细小血管(19%)、血流灌注有限的血管(15%)、存在显著远端病变的血管(24%)或移植部位有严重动脉粥样硬化的血管(22%)。从统计学角度来看,这些闭塞率与总体失败率并无显著差异,也并非移植的绝对禁忌证。术前血管造影显示有一组特殊的血管似乎充盈不足(直径1.5毫米或更小,但管壁光滑且看似健康,供应的心肌面积比其外观尺寸预期的更大)。这些血管在术后血管造影中显示直径显著增加,且闭塞率较低(15例移植血管中有1例;7%)。当所有移植血管均通畅时,术后左心室射血分数的平均值较术前有显著增加,但当有一个或多个移植血管闭塞时,则无显著变化。

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