Partridge J B, Brandt P W, Whitlock R M
Clin Radiol. 1978 Jan;29(1):5-8. doi: 10.1016/s0009-9260(78)80155-x.
In a series of 141 saphenous vein aortocoronary bypass grafts in 59 patients undergoing routine restudy of the coronary arteries within four weeks of operation, an overall graft occlusion rate of 12% was found. A trend towards a higher occlusion rate was seen in arteries that were small (19%), that had a limited run-off (15%), significant distal disease (24%) or severe atheroma at the graft site (22%). Statistically, these occlusion rates are not significantly different from the overall failure rate and do not give absolute contra-indications to grafting. A particular group of arteries which seemed underfilled in the pre-operative angiogram (1.5 mm or less in diameter but apparently healthy with smooth walls and supplying a larger area of myocardium than would be expected from their apparent size) was identified. These arteries showed a significant increase in diameter in the post-operative angiograms and had a low occlusion rate (1 of 15 grafts; 7%). When all grafts were patent, the mean post-operative left ventricular ejection fraction showed a significant increase over the pre-operative valve, but when one or more grafts were occluded there was no significant change.
在对59例患者进行的141例大隐静脉主动脉冠状动脉旁路移植术中,这些患者在术后四周内接受了常规的冠状动脉复查,结果发现总的移植血管闭塞率为12%。在一些血管中可见闭塞率有升高趋势,这些血管包括细小血管(19%)、血流灌注有限的血管(15%)、存在显著远端病变的血管(24%)或移植部位有严重动脉粥样硬化的血管(22%)。从统计学角度来看,这些闭塞率与总体失败率并无显著差异,也并非移植的绝对禁忌证。术前血管造影显示有一组特殊的血管似乎充盈不足(直径1.5毫米或更小,但管壁光滑且看似健康,供应的心肌面积比其外观尺寸预期的更大)。这些血管在术后血管造影中显示直径显著增加,且闭塞率较低(15例移植血管中有1例;7%)。当所有移植血管均通畅时,术后左心室射血分数的平均值较术前有显著增加,但当有一个或多个移植血管闭塞时,则无显著变化。